Quackenbush L J, Dowjat W K, Zaleski M B
Immunol Invest. 1985 Aug;14(4):379-85. doi: 10.3109/08820138509022673.
Twenty-nine different F1 hybrids were tested for the possible effect of the H-2 (I-A) heterozygosity purportedly mediated by I-A trans-complementation, on the magnitude of the anti-Thy-1 response. Although the hybrids tested responded well to immunization with Thy-1 disparate thymocytes from donors H-2 compatible with one of the parents they responded poorly when immunized with thymocytes from donors H-2 incompatible with both parents. Preliminary data suggest that H-2 heterozygosity may exert a small but definite effect in H-2r/H-2f hybrids.
对29种不同的F1杂种进行了测试，以研究据称由I-A反式互补介导的H-2（I-A）杂合性对抗Thy-1反应强度的可能影响。尽管所测试的杂种对来自与亲本之一H-2相容的供体的Thy-1不同胸腺细胞免疫反应良好，但在用来自与双亲H-2都不相容的供体的胸腺细胞免疫时，它们的反应较差。初步数据表明，H-2杂合性可能在H-2r/H-2f杂种中产生微小但确定的影响。
