Kubota K, Sugaya K, Matsuda I, Matsuoka Y, Itonaga M
Jpn J Pharmacol. 1985 Sep;39(1):120-2. doi: 10.1254/jjp.39.120.
Intracisternal administration of caerulein inhibited the food intake in mice, but the caerulein action was antagonized by benzodiazepines such as chlordiazepoxide, diazepam and flurazepam which were administered intraperitoneally in low doses (0.2 to 2 mg/kg). The antagonism mechanism between caerulein and benzodiazepines remains unclear, but the characteristics of the antagonism were similar to those which had been observed with cholecystokinin and benzodiazepines.
向脑池内注射蛙皮素可抑制小鼠的食物摄取，但蛙皮素的作用可被腹腔注射低剂量（0.2至2毫克/千克）的苯二氮卓类药物如氯氮卓、地西泮和氟西泮所拮抗。蛙皮素与苯二氮卓类药物之间的拮抗机制尚不清楚，但这种拮抗作用的特征与胆囊收缩素和苯二氮卓类药物之间所观察到的相似。
