Suppr超能文献

美国大麻合法化以及青少年对电子烟和食用大麻产品的使用。

U.S. cannabis legalization and use of vaping and edible products among youth.

作者信息

Borodovsky Jacob T, Lee Dustin C, Crosier Benjamin S, Gabrielli Joy L, Sargent James D, Budney Alan J

机构信息

Center for Technology and Behavioral Health Geisel School of Medicine at Dartmouth, 46 Centerra Parkway, Lebanon, NH 03766, United States; The Dartmouth Institute for Health Policy and Clinical Practice, Geisel School of Medicine at Dartmouth, 74 College St., Hanover, NH 03755, United States.

Behavioral Pharmacology Research Unit, Johns Hopkins University School of Medicine 5510 Nathan Shock Drive, Baltimore, MD 21224-6823, United States.

出版信息

Drug Alcohol Depend. 2017 Aug 1;177:299-306. doi: 10.1016/j.drugalcdep.2017.02.017. Epub 2017 Jun 9.

Abstract

BACKGROUND

Alternative methods for consuming cannabis (e.g., vaping and edibles) have become more popular in the wake of U.S. cannabis legalization. Specific provisions of legal cannabis laws (LCL) (e.g., dispensary regulations) may impact the likelihood that youth will use alternative methods and the age at which they first try the method - potentially magnifying or mitigating the developmental harms of cannabis use.

METHODS

This study examined associations between LCL provisions and how youth consume cannabis. An online cannabis use survey was distributed using Facebook advertising, and data were collected from 2630 cannabis-using youth (ages 14-18). U.S. states were coded for LCL status and various LCL provisions. Regression analyses tested associations among lifetime use and age of onset of cannabis vaping and edibles and LCL provisions.

RESULTS

Longer LCL duration (OR: 2.82, 95% CI: 2.24, 3.55; OR: 3.82, 95% CI: 2.96, 4.94), and higher dispensary density (OR: 2.68, 95% CI: 2.12, 3.38; OR: 3.31, 95% CI: 2.56, 4.26), were related to higher likelihood of trying vaping and edibles. Permitting home cultivation was related to higher likelihood (OR: 1.93, 95% CI: 1.50, 2.48) and younger age of onset (β: -0.30, 95% CI: -0.45, -0.15) of edibles.

CONCLUSION

Specific provisions of LCL appear to impact the likelihood, and age at which, youth use alternative methods to consume cannabis. These methods may carry differential risks for initiation and escalation of cannabis use. Understanding associations between LCL provisions and methods of administration can inform the design of effective cannabis regulatory strategies.

摘要

背景

在美国大麻合法化之后,吸食大麻的替代方法(例如,吸电子烟和食用大麻制品)变得更加流行。合法大麻法律(LCL)的具体条款(例如,药房规定)可能会影响青少年使用替代方法的可能性以及他们首次尝试该方法的年龄——这可能会放大或减轻大麻使用对发育的危害。

方法

本研究调查了LCL条款与青少年吸食大麻方式之间的关联。通过脸书广告分发了一项在线大麻使用调查,并从2630名吸食大麻的青少年(年龄在14 - 18岁之间)收集了数据。对美国各州的LCL状况和各种LCL条款进行编码。回归分析测试了终生使用情况、大麻吸电子烟和食用大麻制品的开始使用年龄与LCL条款之间的关联。

结果

LCL实施时间越长(比值比:2.82,95%置信区间:2.24,3.55;比值比:3.82,95%置信区间:2.96,4.94),以及药房密度越高(比值比:2.68,95%置信区间:2.12,3.38;比值比:3.31,95%置信区间:2.56,4.26),与尝试吸电子烟和食用大麻制品的可能性越高相关。允许家庭种植与食用大麻制品的可能性较高(比值比:1.93,95%置信区间:1.50,2.48)以及开始使用年龄较小(β: - 0.30,95%置信区间: - 0.45, - 0.15)相关。

结论

LCL的具体条款似乎会影响青少年使用替代方法吸食大麻的可能性以及年龄。这些方法在大麻使用的起始和升级方面可能存在不同风险。了解LCL条款与给药方法之间的关联可为有效的大麻监管策略设计提供参考。

相似文献

4
Emerging Trends in Cannabis Administration Among Adolescent Cannabis Users.青少年大麻使用者中大麻给药方式的新趋势。
J Adolesc Health. 2019 Apr;64(4):487-493. doi: 10.1016/j.jadohealth.2018.07.012. Epub 2018 Sep 8.
6
Online survey characterizing vaporizer use among cannabis users.在线调查描绘了大麻使用者中汽化器的使用情况。
Drug Alcohol Depend. 2016 Feb 1;159:227-33. doi: 10.1016/j.drugalcdep.2015.12.020. Epub 2015 Dec 30.
8
How four U.S. states are regulating recreational marijuana edibles.美国四个州如何监管娱乐用大麻食品。
Int J Drug Policy. 2017 May;43:83-90. doi: 10.1016/j.drugpo.2017.01.018. Epub 2017 Mar 23.
10

引用本文的文献

本文引用的文献

5
Edible Cannabis Products: It Is Time for FDA Oversight.可食用大麻产品:FDA监管的时候到了。
J Clin Pharmacol. 2016 Sep;56(9):1045-7. doi: 10.1002/jcph.778. Epub 2016 Jul 12.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验