Borodovsky Jacob T, Lee Dustin C, Crosier Benjamin S, Gabrielli Joy L, Sargent James D, Budney Alan J
Center for Technology and Behavioral Health Geisel School of Medicine at Dartmouth, 46 Centerra Parkway, Lebanon, NH 03766, United States; The Dartmouth Institute for Health Policy and Clinical Practice, Geisel School of Medicine at Dartmouth, 74 College St., Hanover, NH 03755, United States.
Behavioral Pharmacology Research Unit, Johns Hopkins University School of Medicine 5510 Nathan Shock Drive, Baltimore, MD 21224-6823, United States.
Drug Alcohol Depend. 2017 Aug 1;177:299-306. doi: 10.1016/j.drugalcdep.2017.02.017. Epub 2017 Jun 9.
Alternative methods for consuming cannabis (e.g., vaping and edibles) have become more popular in the wake of U.S. cannabis legalization. Specific provisions of legal cannabis laws (LCL) (e.g., dispensary regulations) may impact the likelihood that youth will use alternative methods and the age at which they first try the method - potentially magnifying or mitigating the developmental harms of cannabis use.
This study examined associations between LCL provisions and how youth consume cannabis. An online cannabis use survey was distributed using Facebook advertising, and data were collected from 2630 cannabis-using youth (ages 14-18). U.S. states were coded for LCL status and various LCL provisions. Regression analyses tested associations among lifetime use and age of onset of cannabis vaping and edibles and LCL provisions.
Longer LCL duration (OR: 2.82, 95% CI: 2.24, 3.55; OR: 3.82, 95% CI: 2.96, 4.94), and higher dispensary density (OR: 2.68, 95% CI: 2.12, 3.38; OR: 3.31, 95% CI: 2.56, 4.26), were related to higher likelihood of trying vaping and edibles. Permitting home cultivation was related to higher likelihood (OR: 1.93, 95% CI: 1.50, 2.48) and younger age of onset (β: -0.30, 95% CI: -0.45, -0.15) of edibles.
Specific provisions of LCL appear to impact the likelihood, and age at which, youth use alternative methods to consume cannabis. These methods may carry differential risks for initiation and escalation of cannabis use. Understanding associations between LCL provisions and methods of administration can inform the design of effective cannabis regulatory strategies.
在美国大麻合法化之后,吸食大麻的替代方法(例如,吸电子烟和食用大麻制品)变得更加流行。合法大麻法律(LCL)的具体条款(例如,药房规定)可能会影响青少年使用替代方法的可能性以及他们首次尝试该方法的年龄——这可能会放大或减轻大麻使用对发育的危害。
本研究调查了LCL条款与青少年吸食大麻方式之间的关联。通过脸书广告分发了一项在线大麻使用调查,并从2630名吸食大麻的青少年(年龄在14 - 18岁之间)收集了数据。对美国各州的LCL状况和各种LCL条款进行编码。回归分析测试了终生使用情况、大麻吸电子烟和食用大麻制品的开始使用年龄与LCL条款之间的关联。
LCL实施时间越长(比值比:2.82,95%置信区间:2.24,3.55;比值比:3.82,95%置信区间:2.96,4.94),以及药房密度越高(比值比:2.68,95%置信区间:2.12,3.38;比值比:3.31,95%置信区间:2.56,4.26),与尝试吸电子烟和食用大麻制品的可能性越高相关。允许家庭种植与食用大麻制品的可能性较高(比值比:1.93,95%置信区间:1.50,2.48)以及开始使用年龄较小(β: - 0.30,95%置信区间: - 0.45, - 0.15)相关。
LCL的具体条款似乎会影响青少年使用替代方法吸食大麻的可能性以及年龄。这些方法在大麻使用的起始和升级方面可能存在不同风险。了解LCL条款与给药方法之间的关联可为有效的大麻监管策略设计提供参考。