Cowall D E, Pasquale D N, Dekker P
Cancer. 1979 May;43(5):1914-6. doi: 10.1002/1097-0142(197905)43:5<1914::aid-cncr2820430549>3.0.co;2-q.
A case of a patient who developed erythroleukemia 3 years into the course of paroxysmal nocturnal hemoglobinuria (PNH) is presented. A case of erythroleukemia with a positive sucrose lysis test has been reported, but our case appears to be the first with a long clinical course of PNH evolving into erythroleukemia. The association between these two diseases, their possible clonal origin, and how they fit into the myelodysplastic syndromes are discussed.
本文报告了1例阵发性夜间血红蛋白尿（PNH）病程3年后发生红白血病的患者。此前有关于蔗糖溶血试验阳性的红白血病病例报道，但我们的病例似乎是首例具有从PNH漫长病程发展为红白血病的患者。文中讨论了这两种疾病之间的关联、它们可能的克隆起源，以及它们如何归入骨髓增生异常综合征。
