Damodaran Mathi, Vienola Kari V, Braaf Boy, Vermeer Koenraad A, de Boer Johannes F
LaserLaB, Department of Physics and Astronomy, Vrije Universiteit Amsterdam, De Boelelaan 1081, 1081 HV Amsterdam, The Netherlands.
Rotterdam Ophthalmic Institute, Schiedamse Vest 160D, 3011 BH Rotterdam, The Netherlands.
Biomed Opt Express. 2017 Apr 28;8(5):2766-2780. doi: 10.1364/BOE.8.002766. eCollection 2017 May 1.
Retinal imaging is demonstrated using a novel scanning light ophthalmoscope based on a digital micromirror device with 810 nm illumination. Concentric circles were used as scan patterns, which facilitated fixation by a human subject for imaging. An annular illumination was implemented in the system to reduce the background caused by corneal reflections and thereby to enhance the signal-to-noise ratio. A 1.9-fold increase in the signal-to-noise ratio was found by using an annular illumination aperture compared to a circular illumination aperture, resulting in a 5-fold increase in imaging speed and a better signal-to-noise ratio compared to our previous system. We tested the imaging performance of our system by performing non-mydriatic imaging on two subjects at a speed of 7 Hz with a maximum 20° (diameter) field of view. The images were shot noise limited and clearly show various anatomical features of the retina with high contrast.
使用基于数字微镜器件且具备810 nm照明的新型扫描光检眼镜进行视网膜成像演示。同心圆用作扫描模式,便于人类受试者注视以进行成像。系统中采用环形照明以减少角膜反射引起的背景,从而提高信噪比。与圆形照明孔径相比,使用环形照明孔径时信噪比提高了1.9倍,成像速度提高了5倍,且与我们之前的系统相比具有更好的信噪比。我们通过以7 Hz的速度、最大20°(直径)视野对两名受试者进行免散瞳成像来测试系统的成像性能。图像受散粒噪声限制,清晰显示出视网膜的各种高对比度解剖特征。