Nakada Mitsutoshi, Tanaka Shingo, Oishi Masahiro, Miyashita Katsuyoshi, Misaki Kouichi, Mohri Masanao, Hayashi Yasuhiko, Uchiyama Naoyuki, Watanabe Takuya, Hayashi Yutaka
Department of Neurosurgery, Graduate School of Medical Science, Kanazawa University, Kanazawa, Ishikawa.
NMC Case Rep J. 2014 Sep 29;2(1):36-39. doi: 10.2176/nmccrj.2014-0080. eCollection 2015 Jan.
Implantation of carmustine-impregnated wafers (Gliadel) into the tumor resection cavity has demonstrated a survival benefit for patients with malignant glioma. However, some precautions should be taken regarding Gliadel implantation. We report a case of a 63-year-old man with glioblastoma who was implanted with Gliadel after a left temporal lobe tumor had been removed, and who later developed vasospasm of the lenticulostriate artery close to the implanted Gliadel, leading to serious cerebral infarction. Therefore, the implantation of Gliadel in cases where important vessels run close to the resection cavity should be considered with great caution.
将卡莫司汀植入片（Gliadel）植入肿瘤切除腔已证明对恶性胶质瘤患者有生存益处。然而，关于Gliadel植入应采取一些预防措施。我们报告一例63岁胶质母细胞瘤男性患者，其在左颞叶肿瘤切除后植入了Gliadel，随后在靠近植入的Gliadel处发生豆纹动脉血管痉挛，导致严重脑梗死。因此，在重要血管靠近切除腔的情况下植入Gliadel应极其谨慎。
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