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[反射疗法及饮用矿泉水对代谢综合征患者的治疗作用机制]

[The mechanisms underlying the therapeutic effects of reflexotherapy and drinking mineral waters in the patients presenting with metabolic syndrome].

作者信息

Zhernov V A, Frolkov V K, Zubarkina M M

机构信息

Federal state autonomous educational institution 'Russian University of Peoples' Friendship', Ministry of Education and Science of the Russian Federation, Miklukho-Maklay str., 6, Moscow, Russian Federation.

Federal state budgetary institution 'Russian Scientific Center of Medical Rehabilitation and Balneology', Ministry of Health of the Russian Federation, Novy Arbat str., 32, Moscow, Russia, 121099.

出版信息

Vopr Kurortol Fizioter Lech Fiz Kult. 2017;94(2):36-41. doi: 10.17116/kurort201794236-41.

DOI:10.17116/kurort201794236-41
PMID:28665380
Abstract

UNLABELLED

Both acupuncture and drinking mineral water can influence the metabolism of carbohydrates and lipids as well as their hormonal regulation, but the possibility of the application of these therapeutic factors for the correction of insulin resistance has not been studied in the patients presenting with metabolic syndrome.

AIM

The objective of the present study was to evaluate the effects produced by the intake of drinking mineral water and acupuncture on the various parameters characterizing the patients suffering from metabolic syndrome in combination with altered insulin resistance.

MATERIAL AND METHODS

Ninety patients with this condition included in the study underwent the analysis of their the blood pressure, body mass index, blood glucose and lipid levels, insulin and cortisol secretion.

RESULTS

We undertook the analysis of the effects of the single and repeated intakes of Essentuki No 17 mineral water included in the combined treatment of the patients with metabolic syndrome and revealed many common responses of the organism to its therapeutic action. Specifically, the stress-type reactions suggested the initiation of the adaptive processes in the system of hormonal regulation of carbohydrate and lipid metabolism. Simultaneously, the manifestations of insulin resistance became less pronounced indicating that both acupuncture and drinking mineral water suppressed the action of the main pathogenic mechanisms underlying the development of metabolic syndrome. Moreover, it was shown that acupuncture had a stronger hypotensive effect in the combination with the decrease of the overproduction of cortisol whereas the intake of the mineral water had a greater metabolic potential and contributed to the intensification of the basal secretion of glucocorticoids. Both reflexotherapy and drinking mineral water have a well apparent effect on the pathogenetic reactions of the metabolic syndrome and therefore can be used in addition to the standard therapy to activate the non-specific, phylogenetically established and enshrined at the genetic level self-healing responses by mainstreaming the adaptation processes and the formation of the adaptive reactions initiated by stressor components.

CONCLUSION

The addition of acupuncture or domestic mineral water intake to the standard therapy of the patients suffering from metabolic syndrome significantly enhances the effectiveness of the treatment. The beneficial therapeutic action of acupuncture and drinking mineral water is underlain by their impact on the mechanisms of resistance to insulin that manifests itself as a decrease of the fasting secretion of this hormone and optimization of carbohydrate and lipid metabolism. The therapeutic effect of acupuncture and drinking mineral water is realized through the induction of the stress-initiating reactions which activate the processes of adaptation, with reflexotherapy largely acting on the cardiovascular system and drinking mineral water on the system responsible for insulin regulation of the metabolic processes.

摘要

未标注

针灸和饮用矿泉水均可影响碳水化合物和脂质的代谢及其激素调节,但对于代谢综合征患者,尚未研究将这些治疗因素应用于改善胰岛素抵抗的可能性。

目的

本研究的目的是评估饮用矿泉水和针灸对代谢综合征合并胰岛素抵抗改变患者的各项特征参数的影响。

材料与方法

纳入本研究的90例该疾病患者接受了血压、体重指数、血糖和血脂水平、胰岛素及皮质醇分泌的分析。

结果

我们分析了在代谢综合征患者联合治疗中单次及重复饮用埃森图基17号矿泉水的效果,发现机体对其治疗作用有许多共同反应。具体而言,应激型反应表明碳水化合物和脂质代谢激素调节系统中适应性过程的启动。同时,胰岛素抵抗的表现变得不那么明显,这表明针灸和饮用矿泉水均抑制了代谢综合征发生发展的主要致病机制的作用。此外,研究表明针灸在降低皮质醇过量分泌的同时具有更强的降压作用,而饮用矿泉水具有更大的代谢潜力,并有助于增强糖皮质激素的基础分泌。反射疗法和饮用矿泉水对代谢综合征的致病反应均有明显作用,因此除标准治疗外,还可用于通过使适应过程主流化以及由应激源成分引发的适应性反应的形成来激活非特异性、系统发育确定且在基因水平固化的自我修复反应。

结论

在代谢综合征患者的标准治疗中添加针灸或饮用国产矿泉水可显著提高治疗效果。针灸和饮用矿泉水的有益治疗作用在于它们对胰岛素抵抗机制的影响,表现为该激素空腹分泌减少以及碳水化合物和脂质代谢的优化。针灸和饮用矿泉水的治疗效果是通过诱导应激引发反应来实现的,这些反应激活了适应过程,反射疗法主要作用于心血管系统,而饮用矿泉水作用于负责胰岛素调节代谢过程的系统。

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