Chatziralli Irini, Theodossiadis George, Brouzas Dimitrios, Theodossiadis Panagiotis
1 2nd Department of Ophthalmology, Attikon Hospital, University of Athens, Athens - Greece.
2 1st Department of Ophthalmology, University of Athens, Athens - Greece.
Eur J Ophthalmol. 2017 Nov 8;27(6):769-773. doi: 10.5301/ejo.5000999.
To study the evolution of subretinal precipitates coexistent with optic disc pit (ODP) maculopathy from their appearance at baseline examination until their absorption after successful treatment.
Participants in this retrospective, multicenter study were 42 patients with ODP maculopathy, in whom complete ocular examination was performed, including visual acuity (VA) measurement, slit-lamp examination, color or red-free fundus photography, and optical coherence tomography at baseline after surgical treatment.
Out of 42 cases, 17 (40.5%) cases of ODP maculopathy, which were examined between 2002 and 2015, were found to have subretinal precipitates associated with multilayer fluid accumulation at baseline. Precipitates were located at the outer part of the photoreceptor layer and remained for 3-6 months after successful treatment and absorption of subretinal fluid. The mean VA was 0.99 ± 0.21 logMAR at baseline and improved to 0.54 ± 0.25 logMAR at the final examination.
Macular precipitates in association with signs of disease chronicity, such as multilayer fluid accumulation, became evident at baseline examination. Precipitates' disappearance in 15 out of 17 cases coincided with the absorption of subretinal fluid. The relative low VA at baseline probably could be attributed to the chronicity of the disease.
研究与视盘小凹(ODP)黄斑病变共存的视网膜下沉淀物从基线检查时出现直至成功治疗后吸收的演变过程。
这项回顾性多中心研究的参与者为42例ODP黄斑病变患者,对其进行了全面的眼部检查,包括视力(VA)测量、裂隙灯检查、彩色或无赤眼底照相以及手术治疗后基线时的光学相干断层扫描。
在42例病例中,2002年至2015年间检查的17例(40.5%)ODP黄斑病变患者在基线时发现有与多层液体积聚相关的视网膜下沉淀物。沉淀物位于光感受器层的外部,在视网膜下液成功治疗并吸收后持续存在3至6个月。基线时平均VA为0.99±0.21 logMAR,最终检查时提高到0.54±0.25 logMAR。
与疾病慢性体征(如多层液体积聚)相关的黄斑沉淀物在基线检查时变得明显。17例中有15例沉淀物的消失与视网膜下液的吸收同时发生。基线时相对较低的VA可能归因于疾病的慢性病程。