Superstein Rosanne, Dean Trevano W, Holmes Jonathan M, Chandler Danielle L, Cotter Susan A, Wallace David K, Melia B Michele, Kraker Raymond T, Weaver R Grey, Mohney Brian G, Donahue Sean P, Birch Eileen E
Centre Hospitalier Universitaire Sainte-Justine, Montreal, Quebec, Canada.
Jaeb Center for Health Research, Tampa, Florida.
J AAPOS. 2017 Aug;21(4):268-273. doi: 10.1016/j.jaapos.2017.04.005. Epub 2017 Jun 28.
To determine the relationships between stereoacuity, control of exotropia, and angle of deviation in children with intermittent exotropia (IXT).
Data collected for 652 participants 3 to <11 years of age with IXT meeting eligibility criteria for enrollment into one of two multicenter, randomized clinical trials were used to evaluate relationships between stereoacuity, control, and angle of deviation at enrollment.
Any level of stereoacuity and angle of deviation could be accompanied by any level of control. Worse distance exotropia control was weakly associated with poorer distance stereoacuity (R = 0.26; 99% CI, 0.17-0.36) and larger angles of deviation at distance (R = 0.27; 99% CI, 0.17-0.36). Worse near exotropia control was weakly associated with poorer near stereoacuity (R = 0.17; 99% CI, 0.07-0.27) and moderately associated with larger angles of deviation at near (R = 0.37; 99% CI, 0.28-0.45). There was no association between stereoacuity and angle of deviation at distance (R = 0.07; 99% CI, -0.03 to 0.17) or at near (R = 0.02; 99% CI, -0.08 to 0.12).
Although weak and moderate associations were found between stereoacuity, control, and angle of deviation, a child may exhibit any combination of stereoacuity, control, and angle of deviation. The specific roles of control, stereoacuity, and angle of deviation in the diagnosis, management, and pathogenesis of IXT are unclear, and each appears to yield somewhat independent information.
确定间歇性外斜视（IXT）患儿的立体视锐度、外斜视控制情况与偏斜角度之间的关系。
收集了652名3至<11岁符合两项多中心随机临床试验之一入组资格标准的IXT参与者的数据，用于评估入组时立体视锐度、控制情况和偏斜角度之间的关系。
任何水平的立体视锐度和偏斜角度都可能伴有任何水平的控制情况。远距离外斜视控制较差与远距离立体视锐度较差（R = 0.26；99%CI，0.17 - 0.36）以及远距离较大的偏斜角度（R = 0.27；99%CI，0.17 - 0.36）弱相关。近距离外斜视控制较差与近距离立体视锐度较差（R = 0.17；99%CI，0.07 - 0.27）弱相关，与近距离较大的偏斜角度中度相关（R = 0.37；99%CI，0.28 - 0.45）。远距离（R = 0.07；99%CI， - 0.03至0.17）或近距离（R = 0.02；99%CI， - 0.08至0.12）的立体视锐度与偏斜角度之间无关联。
尽管在立体视锐度、控制情况和偏斜角度之间发现了弱和中度关联，但儿童可能表现出立体视锐度、控制情况和偏斜角度的任何组合。控制情况、立体视锐度和偏斜角度在IXT的诊断、管理和发病机制中的具体作用尚不清楚，而且每种因素似乎都能提供 somewhat 独立的信息。 （注：“somewhat”直译为“有点”，结合语境此处不太好确切翻译出合适词汇，故保留英文）
