School of Medicine, Konkuk University, Seoul, Republic of Korea.
Department of Ophthalmology, Seoul National University Hospital and Seoul National University College of Medicine, Seoul, Republic of Korea.
BMC Ophthalmol. 2023 Apr 26;23(1):185. doi: 10.1186/s12886-023-02919-z.
Patients with strabismus are more likely to have mental health problems, including high rates of depressive symptoms and social phobia. Intermittent exotropia (IXT) typically occurs in early childhood and is more common in Asian populations. We aim to assess the health-related quality of life (HRQOL) concerns in children with intermittent exotropia (IXT) using the Intermittent Exotropia Questionaire (IXTQ), and their associations with the clinical severity of IXT and the parents' HRQOL concerns.
IXT, defined as both distance and near exodeviation ≥ 10 prism diopters were eligible for inclusion. The final IXTQ score is calculated using the mean score for all items, and ranges from 0 (worst HRQOL) to 100 (best HRQOL). The correlations of child IXTQ scores with their deviation angle and stereoacuity were measured, as were those with their parent's IXTQ scores.
One hundred twenty-two children with IXT (aged 5-17 years) and one parent for each child completed the child and parent IXTQ, respectively. The greatest HRQOL concern for each child with IXT and their parent was "Worry about eyes" (frequency 88%, score 35.0 ± 27.8). Lower child IXTQ scores were associated with a larger distance (r = 0.24, p = 0.007) and near deviation angle (r = 0.2, p = 0.026). "It bothers me because I have to wait for my eyes to clear up" and "Waiting for their eyes to clear up" were more common in children with a larger deviation angle (both p < 0.05). The parent IXTQ scores (52.1 ± 25.3) were lower than the child ones (79.7 ± 15.8) and showed a positive correlation with child IXTQ scores (r = 0.26, p = 0.004). Lower parent IXTQ scores were associated with poor distance stereoacuity (r = 0.23, p = 0.01).
The HRQOL of IXT children was positively related to that of their parents. A larger deviation angle and worse distance stereoacuity function may predict more-negative impacts on children and their parents, respectively.
斜视患者更容易出现心理健康问题,包括抑郁症状和社交恐惧症的高发率。间歇性外斜视(IXT)通常发生在儿童早期,在亚洲人群中更为常见。我们旨在使用间歇性外斜视问卷(IXTQ)评估间歇性外斜视(IXT)儿童的健康相关生活质量(HRQOL)问题,并评估其与 IXT 的临床严重程度以及父母的 HRQOL 问题的相关性。
符合纳入标准的患者为双眼距离和近距外斜视均≥10 棱镜度的间歇性外斜视患者。最终的 IXTQ 评分是通过所有项目的平均得分计算得出的,范围从 0(最差 HRQOL)到 100(最佳 HRQOL)。测量了患儿 IXTQ 评分与斜视角度和立体视锐度的相关性,以及与父母 IXTQ 评分的相关性。
122 名患有间歇性外斜视的儿童(年龄 5-17 岁)及其每位儿童的一名家长分别完成了儿童和家长的 IXTQ。每个患有间歇性外斜视的儿童及其父母最关心的 HRQOL 问题是“担心眼睛”(频率 88%,得分 35.0±27.8)。较低的患儿 IXTQ 评分与较大的距离(r=0.24,p=0.007)和近距斜视角度(r=0.2,p=0.026)相关。“斜视让我很困扰,因为我得等我的眼睛恢复正常”和“等待他们的眼睛恢复正常”在斜视角度较大的儿童中更为常见(均 p<0.05)。父母的 IXTQ 评分(52.1±25.3)低于儿童的 IXTQ 评分(79.7±15.8),且与儿童的 IXTQ 评分呈正相关(r=0.26,p=0.004)。较低的父母 IXTQ 评分与较差的距离立体视锐度相关(r=0.23,p=0.01)。
IXT 患儿的 HRQOL 与其父母的 HRQOL 呈正相关。较大的斜视角度和较差的距离立体视锐度可能分别预示着患儿和其父母的负面影响更大。