Vinogradova M S
Biull Eksp Biol Med. 1985 Dec;100(12):736-8.
Light microscopy was applied to study variation in the composition and number of apudocytes in the gastric epithelium of red-cheeked sousliks over time. During hibernation, the content of serotonin-producing EC cells was elevated. This is in agreement with serotonin involvement in the maintenance of the hibernation state. The number of non-EC cells taking part in digestion, which does not occur during hibernation, was lowered. Spring awakening was accompanied with an increase in the number of non-EC cells and the lack of significant changes in cells. In souslics, which were active in winter, the content of non-cells was high, since the animals continued feeding on, and the content of EC-cells was elevated similarly to that in hibernating animals, which could be explained by genetic dependence. The number of apudocytes in the gastric mucosa was discovered to correlate in the main with the features of their function at different seasons.
运用光学显微镜研究了红颊黄鼠胃上皮中APUD细胞的组成和数量随时间的变化。在冬眠期间,产生5-羟色胺的肠嗜铬(EC)细胞含量升高。这与5-羟色胺参与维持冬眠状态相一致。参与消化的非EC细胞数量减少,因为冬眠期间不发生消化过程。春季苏醒伴随着非EC细胞数量的增加,且细胞无显著变化。在冬季活跃的黄鼠中,非EC细胞的含量很高,因为动物继续进食,且EC细胞的含量与冬眠动物相似也有所升高,这可能是由遗传依赖性所解释的。发现胃黏膜中APUD细胞的数量主要与它们在不同季节的功能特征相关。