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[冬眠啮齿动物胃黏膜上皮有丝分裂活性变化的年度周期]

[Annual cycle of the changes in the mitotic activity of gastric mucosal epithelium in hibernating rodents].

作者信息

Vinogradova M S

出版信息

Biull Eksp Biol Med. 1982 May;93(5):91-3.

PMID:7093517
Abstract

It was shown that mitotic activity of the gastric mucosa epithelium in Citelius erythrogenus Br. is characterized by pronounced seasonal changes. The highest mitotic index was recorded 3-4 days after the arousal from hibernation, while the lowest one during summer time (May-June). The mitoses are blocked during winter torpor. The circadian peak of the mitotic activity in summer was recorded at 10 p.m. The mitotic cells were discovered not only in the generative zone but also at all the levels of the fundal and pyloric glands. Radioautography with 3H-thymidine administration in vivo is not fit for studying the synthesis of DNA in sousliks.

摘要

结果表明,红尾黄鼠胃黏膜上皮的有丝分裂活性具有明显的季节性变化。有丝分裂指数最高值出现在冬眠苏醒后3 - 4天,而最低值出现在夏季(5 - 6月)。冬季蛰伏期间有丝分裂被阻断。夏季有丝分裂活性的昼夜高峰出现在晚上10点。有丝分裂细胞不仅在生发区被发现,在胃底腺和幽门腺的各个层面也有发现。体内注射³H - 胸腺嘧啶核苷进行放射自显影不适用于研究黄鼠体内DNA的合成。

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