Raafat Eleeza, Karunasiri Deepthi, Kamangar Nader
Department of Medicine, UCLA Medical Center Olive View, Sylmar, California, USA.
Department of Pathology and Laboratory Medicine, UCLA Medical Center Olive View, Pathology and Laboratory Medicine, University of California, Los Angeles David Geffen, School of Medicine, Sylmar, California, USA.
BMJ Case Rep. 2017 Jun 30;2017:bcr-2017-220695. doi: 10.1136/bcr-2017-220695.
Solitary fibrous tumours (SFTs) are relatively rare neoplasms thought to originate from the submesothelial connective tissue. SFTs have been described in a variety of sites, including the pleura, orbit, lower respiratory tract, peritoneal cavity and heart. These neoplasms are usually benign, though locally aggressive, and metastatic behaviour has been observed in some cases. We describe a case of a 61-year-old man presenting with weight loss, poor appetite, malaise, worsening dyspnoea on exertion and lower extremity oedema, who was found to have a gigantic-21×21 cm-tumour occupying the entire right hemithorax causing compression and displacement of the mediastinum and liver. Transthoracic CT-guided biopsy revealed SFT of the pleura. The patient underwent preoperative angiography and embolisation of the tumour followed by successful surgical resection via thoracotomy.
孤立性纤维瘤(SFTs)是相对罕见的肿瘤,被认为起源于间皮下结缔组织。SFTs已在多种部位被描述,包括胸膜、眼眶、下呼吸道、腹膜腔和心脏。这些肿瘤通常是良性的,尽管具有局部侵袭性,并且在某些病例中观察到了转移行为。我们描述了一例61岁男性患者,表现为体重减轻、食欲减退、全身不适、活动时呼吸困难加重和下肢水肿,发现其有一个巨大的(21×21 cm)肿瘤占据整个右半胸,导致纵隔和肝脏受压及移位。经胸CT引导下活检显示为胸膜SFT。患者接受了术前血管造影和肿瘤栓塞,随后通过开胸手术成功切除肿瘤。