Gil Archila Elizabeth, Cuca Suárez Luis Enrique
a Departamento de Química , Pontificia Universidad Javeriana , Bogotá DC , Colombia.
b Facultad de Ciencias, Departamento de Química, Laboratorio de Investigación en Productos Naturales Vegetales , Universidad Nacional de Colombia , Bogotá DC , Colombia.
Nat Prod Res. 2018 Jan;32(2):195-201. doi: 10.1080/14786419.2017.1344663. Epub 2017 Jul 3.
This first phytochemical study of leaves of Ocotea caudata led to the isolation of ten isoquinoline alkaloids, one of them previously unreported, S-(+)-9-O-demethylnorpreocoteine (1), three known flavonoids, two phenols, two eudesmane type sesquiterpenoids, one proline derivative, one fatty alcohol and a phytosterol. Their structures were elucidated on the basis of extensive 1D and 2D NMR spectroscopic analyses including HSQC, HMBC, H-H COSY, NOESY, as well as HRESIMS data in addition to comparison with reports in the literature.
对尾叶樟树叶进行的首次植物化学研究，分离出了10种异喹啉生物碱，其中一种为之前未报道的S-(+)-9-O-去甲基降前樟碱（1）、3种已知黄酮类化合物、2种酚类、2种桉叶烷型倍半萜、1种脯氨酸衍生物、1种脂肪醇和1种植物甾醇。除与文献报道进行比较外，还通过广泛的一维和二维核磁共振光谱分析（包括HSQC、HMBC、H-H COSY、NOESY）以及高分辨电喷雾电离质谱数据对它们的结构进行了阐明。
