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樟科倍半萜和二萜的化学特性及其多方面的健康益处:综述

Chemical characteristics of the sesquiterpenes and diterpenes from Lauraceae family and their multifaceted health benefits: A review.

作者信息

Feng Haowei, Jiang Yiping, Cao Huihui, Shu Yuqi, Yang Xiaoyu, Zhu Daoqi, Shao Meng

机构信息

Guangdong Provincial Key Laboratory of Chinese Medicine Pharmaceutics, School of Traditional Chinese Medicine, Southern Medical University, Guangzhou 510515, China.

Department of Pharmacy, Zhuhai People's Hospital (Zhuhai Hospital Affiliated with Jinan University), Zhuhai 519000, China.

出版信息

Heliyon. 2022 Dec 7;8(12):e12013. doi: 10.1016/j.heliyon.2022.e12013. eCollection 2022 Dec.

Abstract

Lauraceae is a large family with significant economic and medicinal value. Bioactive ingredients from Lauraceae plants have contributed greatly to medicines, food nutrients and fine chemical products. In recent years, quite a few sesquiterpenes and diterpenes with unique structures have been achieved from Lauraceae and their potential benefits are embodied in a wide range of health areas. To our knowledge, there is no review to summarizes these constituents and their biological effects systematically. This current work aims to classify and ascribe the structural types and bioactivities of the identified sesquiterpenes and diterpenes. Herein, a total of 362 sesquiterpenes and 69 diterpenes were comprehensively complied. The various bioactivities could be recognized as cytotoxicity, anti-proliferation and/or anti-apoptosis, anti-inflammation, anti-oxidation, anti-bacterium, etc. This updated data could serve as a catalysis of these sesquiterpenes and diterpenes for the future medical and industrial applications.

摘要

樟科是一个具有重要经济和药用价值的大科。樟科植物中的生物活性成分对药物、食品营养成分和精细化工产品贡献巨大。近年来,已从樟科植物中获得了不少具有独特结构的倍半萜和二萜,它们的潜在益处体现在广泛的健康领域。据我们所知,尚无综述对这些成分及其生物学效应进行系统总结。本研究旨在对已鉴定的倍半萜和二萜的结构类型及生物活性进行分类和归属。在此,共全面整理了362种倍半萜和69种二萜。这些生物活性包括细胞毒性、抗增殖和/或抗凋亡、抗炎、抗氧化、抗菌等。这些更新的数据可为这些倍半萜和二萜未来的医学和工业应用提供助力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fbf5/9801090/2710227b2fc0/gr1.jpg

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