Chacko Praveen, Jayaprakash Kesavapillai, Misiriya Kamarudheenkunju Jameelabeevi Raihanathul, Madhavan Suresh, Kumary Vasantha Sudha, Jayaprasad Narayanapillai, Jayaprakash Vaikathusseril Lembodaran, George Raju
Department of Cardiology, Government Medical College, Kottayam, Kerala, India.
Proc (Bayl Univ Med Cent). 2017 Jul;30(3):273-275. doi: 10.1080/08998280.2017.11929613.
Thrombus exerts a major impact on the performance and outcome of primary and rescue interventions in acute ST-elevation myocardial infarction. Although the optimal treatment of thrombotic lesions is still controversial, thrombus aspiration provides an effective method to achieve successful reperfusion during primary angioplasty. We compared clinical and angiographic outcomes in 286 patients with acute ST-elevation myocardial infarction undergoing primary percutaneous transluminal coronary angioplasty (PTCA) and thrombus aspiration with those who underwent conventional PTCA without thrombus aspiration. Thrombus aspiration during primary percutaneous coronary intervention in patients with high thrombus burden resulted in better Thrombolysis in Myocardial Infarction (TIMI) 3 flow in the infarct-related artery and helped achieve faster ST-segment resolution on the electrocardiogram compared with conventional angioplasty without thrombus aspiration.
血栓对急性ST段抬高型心肌梗死的初次及补救性干预的操作过程及结果有着重大影响。尽管血栓性病变的最佳治疗方法仍存在争议，但血栓抽吸术为在初次血管成形术中实现成功再灌注提供了一种有效方法。我们比较了286例行初次经皮腔内冠状动脉成形术（PTCA）及血栓抽吸术的急性ST段抬高型心肌梗死患者与286例行常规PTCA且未行血栓抽吸术的患者的临床及血管造影结果。与未行血栓抽吸术的传统血管成形术相比，高血栓负荷患者在初次经皮冠状动脉介入治疗期间进行血栓抽吸术可使梗死相关动脉获得更好的心肌梗死溶栓（TIMI）3级血流，并有助于在心电图上更快地实现ST段回落。
