Saad Saadeddine, Mansouri Bobbak, Housewright Chad
Texas A&M College of Medicine Health Science Center (Saad, Mansouri, Housewright) and the Department of Dermatology, Scott and White Hospital (Mansouri, Housewright), Temple, Texas.
Proc (Bayl Univ Med Cent). 2017 Jul;30(3):333. doi: 10.1080/08998280.2017.11929637.
Imiquimod activates the immune system when applied to a local area. We report a patient with a history of well-controlled myasthenia gravis who was prescribed imiquimod for lentigo maligna. Treatment was halted after 2 weeks when the patient reported itching and irritating sensations in his throat, consistent with previous myasthenia exacerbations. The symptoms improved once imiquimod use was discontinued. We advise clinicians to be cautious when prescribing imiquimod to a patient with a history of myasthenia gravis.
咪喹莫特应用于局部区域时会激活免疫系统。我们报告了一名重症肌无力病情一直控制良好的患者，其因恶性雀斑样痣而被开了咪喹莫特。2周后患者报告喉咙有瘙痒和刺激感，这与之前的重症肌无力加重情况一致，于是停止了治疗。停用咪喹莫特后症状有所改善。我们建议临床医生在给有重症肌无力病史的患者开咪喹莫特时要谨慎。
