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角质形成细胞癌的管理——老年人的特殊考虑因素

Management of keratinocyte carcinoma - Special considerations in the elderly.

作者信息

Bailey Alison, Vasicek Brooke, Tao Joy, Janeczek Monica, Mitri Andia, Tung Rebecca

机构信息

Loyola University Chicago, Stritch School of Medicine, Chicago, Illinois.

Loyola University Chicago, Division of Dermatology, Chicago, Illinois.

出版信息

Int J Womens Dermatol. 2019 May 18;5(4):235-245. doi: 10.1016/j.ijwd.2019.05.005. eCollection 2019 Sep.

Abstract

Keratinocyte carcinomas (KCs) are now an epidemic in The United States of America, especially in elderly patients. KCs, including basal cell carcinoma and squamous cell carcinoma, can lead to disfigurement and occasionally death. However, the lower mortality rate associated with KC compared with melanoma allows for increased flexibility in the selection of treatment. Flexibility in treatment is particularly important in the elderly given that this patient population often has medical comorbidities that should be considered. These patients may have multiple KCs, higher risk tolerance to recurrence, and different concerns about cosmetic outcomes compared with their younger counterparts. We review treatment options for KCs and how the selection of each option may affect the elderly patient.

摘要

角质形成细胞癌(KCs)如今在美国呈流行态势,在老年患者中尤为常见。KCs包括基底细胞癌和鳞状细胞癌,可导致毁容,偶尔还会致人死亡。然而,与黑色素瘤相比,KCs的死亡率较低,这使得在治疗选择上有了更大的灵活性。鉴于老年患者群体往往存在需要考虑的合并症,治疗的灵活性在老年患者中尤为重要。与年轻患者相比,这些患者可能有多个KCs,对复发的风险耐受性更高,且对美容效果有不同的关注点。我们综述了KCs的治疗选择以及每种选择的选用如何影响老年患者。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4802/6831749/45bfc4dd18be/gr1.jpg

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