Veit Kaleb
Department of Internal Medicine, the University of Oklahoma School of Community Medicine, Tulsa, Oklahoma.
Proc (Bayl Univ Med Cent). 2017 Jul;30(3):346-347. doi: 10.1080/08998280.2017.11929643.
Vitamin B12 deficiency may present as pseudothrombotic microangiopathy. Pseudothrombotic microangiopathy is anemia, thrombocytopenia, and schistocytosis caused by vitamin B12 deficiency. Pseudothrombotic microangiopathy may be mistaken for microangiopathic hemolytic anemia, confounding appropriate treatment. Evaluation of lactate dehydrogenase, reticulocyte count, bilirubin, and platelet count are most helpful in differentiating pseudothrombotic microangiopathy from a true microangiopathic hemolytic anemia. A case of pseudothrombotic microangiopathy due to severe vitamin B12 deficiency is presented.
维生素B12缺乏可能表现为假性血栓性微血管病。假性血栓性微血管病是由维生素B12缺乏引起的贫血、血小板减少和裂片红细胞症。假性血栓性微血管病可能被误诊为微血管病性溶血性贫血，从而混淆适当的治疗。评估乳酸脱氢酶、网织红细胞计数、胆红素和血小板计数对区分假性血栓性微血管病与真正的微血管病性溶血性贫血最有帮助。本文介绍了一例因严重维生素B12缺乏导致的假性血栓性微血管病病例。
