Check J H, Wu C H, Adelson H G
Int J Fertil. 1985;30(3):45-7.
A study was designed to see if progesterone support of the luteal phase could reduce the increased incidence of spontaneous abortions seen in HMG-induced pregnancies. Fifty milligrams per day of progesterone suppositories beginning on the third day of the temperature rise or the demonstration of ovum release by ultrasound was employed. The incidence of spontaneous abortions in the untreated control group was 28% (28 of 100) as compared to 16% (21 of 130) of the progesterone-supported patients. The decrease in abortions cannot be attributed to losses of multiple gestations since there were larger numbers of multiples in the progesterone-supported group (1.3 babies per patient) versus the controls (1.2 babies per patient).
一项研究旨在观察黄体期补充孕酮是否能降低在人绝经期促性腺激素（HMG）诱导的妊娠中出现的自然流产发生率升高的情况。从体温升高的第三天或通过超声证实卵子排出开始，每天使用50毫克孕酮栓剂。未治疗的对照组自然流产发生率为28%（100例中有28例），而接受孕酮支持治疗的患者为16%（130例中有21例）。流产率的降低不能归因于多胎妊娠的减少，因为与对照组（每位患者1.2个胎儿）相比，接受孕酮支持治疗的组中多胎妊娠数量更多（每位患者1.3个胎儿）。
