Liao Xian-Zhen, Shi Ju-Fang, Liu Jing-Shi, Huang Hui-Yao, Guo Lan-Wei, Zhu Xin-Yu, Xiao Hai-Fan, Wang Le, Bai Ya-Na, Liu Guo-Xiang, Mao A-Yan, Ren Jian-Song, Sun Xiao-Jie, Mai Ling, Liu Yu-Qin, Song Bing-Bing, Gong Ji-Yong, Zhou Jin-Yi, Du Ling-Bing, Zhou Qi, Cao Rong, Zhu Lin, Ren Ying, Lou Pei-An, Lan Li, Sun Xiao-Hua, Qi Xiao, Wang Yuan-Zheng, Zhang Kai, He Jie, Dai Min
Hunan Cancer Hospital, Changsha, China.
National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Asia Pac J Clin Oncol. 2018 Jun;14(3):167-178. doi: 10.1111/ajco.12703. Epub 2017 Jul 3.
We aimed to assess economic burden of breast cancer (BC) diagnosis and treatment in China through a multicenter cross-sectional study, and to obtain theoretical evidence for policy-making.
This survey was conducted in 37 hospital centers across 13 provinces in China from September 2012 to December 2014. We collected information on the subject characteristics. We then assessed the medical and non-medical expenditure for BC diagnosis and treatment, factors influencing the average case expense, variations between medical and non-medical expenditure at different clinical stages, economic impact of overall expenditure in newly diagnosed course after reimbursement to the patient's family, composition of non-medical expenditure and time loss for the patient and family.
Among 2746 women with BC (72.6% were admitted to specialized hospitals), the overall average expenditure was US $8450 (medical expenditure: $7527; non-medical expenditure: $922). Significant differences were found among the overall expenditure in the four clinical stages (P < 0.0001); the expenditure was higher in stages III and IV than that in stages I and II, whereas the stage IV was the highest (P < 0.0001). Moreover, a higher self-reported predicted reimbursement ratio was associated with a less economic impact on the patient's family, and the average time lost was estimated as $1529.
Early detection and treatment of breast cancer might be effective for decreasing the economic burden, because costs escalate as the degree of malignancy increases.
我们旨在通过一项多中心横断面研究评估中国乳腺癌(BC)诊断和治疗的经济负担,并为政策制定获取理论依据。
本调查于2012年9月至2014年12月在中国13个省份的37家医院中心进行。我们收集了受试者特征信息。然后我们评估了乳腺癌诊断和治疗的医疗和非医疗支出、影响平均病例费用的因素、不同临床阶段医疗和非医疗支出的差异、报销后新诊断病程中总支出对患者家庭的经济影响、非医疗支出的构成以及患者和家庭的时间损失。
在2746例乳腺癌女性患者中(72.6%入住专科医院),总平均支出为8450美元(医疗支出:7527美元;非医疗支出:922美元)。四个临床阶段的总支出存在显著差异(P<0.0001);III期和IV期的支出高于I期和II期,而IV期最高(P<0.0001)。此外,自我报告的预测报销比例越高,对患者家庭的经济影响越小,平均时间损失估计为1529美元。
乳腺癌的早期发现和治疗可能对减轻经济负担有效,因为随着恶性程度增加成本会上升。