Xue Li-Wei, Chen Xiao, Yin Dan-Dan, Wang Xu-Xia
Department of Oral and Maxillofacial Surgery, College and Hospital of Stomatology (Shandong Provincial Key Laboratory of Oral Biomedicine), Shandong University, Jinan, China / Department of Oral and Maxillofacial Surgery, Weifang People's Hospital, Weifang, China.
Department of Prosthodontics, Weifang Stomatology Hospital, Weifang, China.
Pak J Pharm Sci. 2017 May;30(3(Special)):1191-1194.
Small cell neuroendocrine carcinoma (SCNEC) of the tongue is very rare. We here present a SCNEC impatient with distant metastasis. A 74-year-old Chinese male went to hospital to treat a tongue tumor, which was founded at a conventional physical examination in Weifang Stomatology Hospital. The check of positron emission tomography-computer tomography (PET-CT) by Weifang people's hospital revealed a tumor in the right root of tongue, and distant metastasis in the right submandibular area, neck, mediastinum, right hilar, abdominal, retroperitoneal multiple lymph nodes, left thyroid, right lower lung, right scapula and bilateral adrenal. The patient was diagnosed tongue SCNEC by the pathological analysis of the tissue section. Conforming to the diagnosis of tongue SCNEC, the patient received adjuvant chemotherapy for 6 cycles with etoposide and carboplatin, and is alive now 9 months after the diagnosis.
舌部小细胞神经内分泌癌(SCNEC)非常罕见。我们在此报告一例伴有远处转移的舌部SCNEC患者。一名74岁的中国男性因舌部肿瘤前往医院就诊,该肿瘤是在潍坊口腔医院的常规体检中发现的。潍坊市人民医院的正电子发射断层扫描 - 计算机断层扫描(PET - CT)检查显示舌右侧根部有肿瘤,右侧颌下区、颈部、纵隔、右肺门、腹部、腹膜后多发淋巴结、左甲状腺、右下肺、右肩胛骨及双侧肾上腺有远处转移。通过组织切片的病理分析,该患者被诊断为舌部SCNEC。符合舌部SCNEC的诊断后,患者接受了依托泊苷和卡铂辅助化疗6个周期,诊断后9个月仍存活。