Zeng Chunyuan, Ling Xueying, Tang Yongjin, Xu Hao
Department of Nuclear Medicine, the First Affiliated Hospital of Jinan University, Guangzhou, Guangdong Province, 510630, China.
Radiol Case Rep. 2022 Mar 3;17(5):1491-1495. doi: 10.1016/j.radcr.2021.12.040. eCollection 2022 May.
Neuroendocrine carcinoma (NEC) involving the tongue is a rare and aggressive disease that is more common in middle-aged and elderly males. We report a case of a 56-year-old male who presented to our hospital with sore throat and was found to have a mass in the left root of the tongue. F-FDG PET/CT revealed intense FDG uptake in the mass of the tongue base, as well as different uptake of FDG in the mid-posterior mediastinal mass, right adrenal gland, and enlarged lymph nodes in the neck and mediastinum. Gadolinium-enhanced MRI clearly showed the extent of the tongue lesion, additionally suggesting the presence of brain metastases. F-FDG PET/MRI fusion images of the neck were obtained on the workstation, which may have a higher diagnostic value for tongue NEC. The patient underwent a biopsy of the mass in the left root of the tongue and was pathologically diagnosed with NEC. Whole-body F-FDG PET/CT and regional PET/MRI fusion images have complementary roles in the diagnosis of tongue NEC, and the former is mainly applied to determine the clinical stage of the disease and to guide treatment.
累及舌部的神经内分泌癌（NEC）是一种罕见且侵袭性强的疾病，在中老年男性中更为常见。我们报告一例56岁男性患者，因咽痛就诊于我院，检查发现舌根部有一肿物。F-FDG PET/CT显示舌根肿物处有强烈的FDG摄取，以及中后纵隔肿物、右侧肾上腺、颈部和纵隔肿大淋巴结处有不同程度的FDG摄取。钆增强MRI清晰显示了舌部病变范围，还提示存在脑转移。在工作站上获取了颈部的F-FDG PET/MRI融合图像，其对舌部NEC可能具有更高的诊断价值。患者接受了舌根部肿物活检，病理诊断为NEC。全身F-FDG PET/CT和局部PET/MRI融合图像在舌部NEC的诊断中具有互补作用，前者主要用于确定疾病的临床分期并指导治疗。
