Wan B Y, Gottfried S
J Pharm Pharmacol. 1985 Oct;37(10):739-41. doi: 10.1111/j.2042-7158.1985.tb04956.x.
Carbenoxolone produced a marked and dose-related inhibition of ethanol-induced gastric lesions in rats. This cytoprotective action was inhibited progressively and significantly by increasing doses of indomethacin. The evidence presented confirms previous suggestions that prostaglandin(s) are involved in the cytoprotective action of carbenoxolone.
生胃酮对大鼠乙醇诱导的胃损伤产生显著且与剂量相关的抑制作用。吲哚美辛剂量增加时，这种细胞保护作用会逐渐且显著地受到抑制。所提供的证据证实了先前的推测，即前列腺素参与了生胃酮的细胞保护作用。
