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开发新的平台化学品:新型生物基分子要成为生物经济中的平台化学品需要什么?

Developing new platform chemicals: what is required for a new bio-based molecule to become a platform chemical in the bioeconomy?

机构信息

School of Chemistry, Federal University of Rio de Janeiro, Brazil.

出版信息

Faraday Discuss. 2017 Sep 21;202:213-225. doi: 10.1039/c7fd00052a.

Abstract

This paper proposes a framework with six dimensions that can be useful for evaluating the potential and the current stage of a bio-based platform chemical. The framework considers the technological and strategic challenges to be fulfilled by a company that intends to lead a platform based on a bio-based chemical. A platform chemical should be an intermediate molecule, with a structure able to generate a number of derivatives, that is produced at a competitive cost, capable of allowing exploitation of the scale and scope economies, and inserted within a complete innovation ecosystem that is able to create value with governance mechanisms that are capable of allowing coordination of the innovation process and facilitation of the value capture by the focal company leading the platform, in our case the producer of the platform molecule. Based on these six dimensions, three potential platform chemicals - succinic acid, butanol and farnesene - are compared and discussed. It is possible to identify important differences concerning the technological dimensions and the strategic dimensions as well. Two of the molecules - farnesene and succinic acid - adhere to most of the conditions required to structure a platform chemical. However, the innovation ecosystem is not complete and the governance mechanisms are still under development, so it is not clear if they will be capable of allowing a favorable position for value capture by the platform leader. Butanol structuring for a platform does not seem promising. The potential of the molecule is apparently not high and the strategic initiatives are in general not focused on innovation ecosystem structuring.

摘要

本文提出了一个具有六个维度的框架,可用于评估生物基平台化学品的潜在和当前阶段。该框架考虑了旨在引领基于生物化学品的平台的公司需要应对的技术和战略挑战。平台化学品应该是一种中间分子,其结构能够生成许多衍生物,以具有竞争力的成本生产,能够利用规模经济和范围经济,并且嵌入到完整的创新生态系统中,该系统能够利用治理机制创造价值,从而协调创新过程并促进主导平台的焦点公司(在我们的案例中为平台分子的生产者)捕获价值。基于这六个维度,对三种潜在的平台化学品(琥珀酸、丁醇和法呢烯)进行了比较和讨论。可以确定在技术维度和战略维度方面存在重要差异。其中两种分子 - 法呢烯和琥珀酸 - 符合构建平台化学品所需的大多数条件。然而,创新生态系统并不完整,治理机制仍在发展中,因此尚不清楚它们是否能够为平台领导者创造有利的价值捕获地位。但是将丁醇构建为平台似乎并不乐观。该分子的潜力显然不高,并且总体战略举措并未专注于创新生态系统的构建。

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