Jin Mingwei, An Qi, Wang Lei
Department of Pediatric Internal Medicine, Xuzhou Children's Hospital, Xuzhou, Jiangsu 221002, P.R. China.
Exp Ther Med. 2017 Jul;14(1):478-482. doi: 10.3892/etm.2017.4526. Epub 2017 May 31.
The health problems related to the nervous system are on rise in young infants leading to high mortality amongst this age group. A chronic medical condition (CC) is present in this age group to the tune of 10-20%. We searched the electronic database PubMed for pre-clinical as well as clinical controlled trials reporting variable chronic conditions especially in pediatric patients. Most of these reports revealed that type 1 diabetes mellitus is the most common CC in young infants. In female patients, metabolic control is often disturbed during CC in this age group. Poor metabolism regulation often results in long-term complications, including cognitive disorders. In cognitive disorders, memory loss and learning problems are the most among adolescents. Executive problems are observed to be associated with low physical activities. The review article concludes that knowledge about factors influencing treatment adherence is crucial in chronically ill infants. Further, we should focus on protective factors in order to prevent health risk behavior.
与神经系统相关的健康问题在幼儿中呈上升趋势,导致该年龄组死亡率居高不下。该年龄组中约10%至20%的儿童患有慢性疾病(CC)。我们在电子数据库PubMed中搜索了报告各种慢性病的临床前及临床对照试验,尤其是儿科患者的试验。这些报告大多显示,1型糖尿病是幼儿中最常见的CC。在该年龄组的女性患者中,慢性病期间代谢控制常常受到干扰。代谢调节不良往往会导致包括认知障碍在内的长期并发症。在认知障碍中,青少年中记忆力丧失和学习问题最为常见。观察到执行问题与低体力活动有关。这篇综述文章得出结论,了解影响治疗依从性的因素对慢性病患儿至关重要。此外,我们应关注保护因素以预防健康风险行为。