Liu Hao, Chen Weikai, Liu Tao, Meng Bin, Yang Huilin
Department of Orthopaedic Surgery, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, People's Republic of China.
J Orthop Surg (Hong Kong). 2017 May-Aug;25(2):2309499017718901. doi: 10.1177/2309499017718901.
To investigate the accuracy of pedicle screw placement based on preoperative computed tomography in comparison with intraoperative data set acquisition for spinal navigation system.
The PubMed (MEDLINE), EMBASE, and Web of Science were systematically searched for the literature published up to September 2015. This review followed the Preferred Reporting Items for Systematic Reviews and Meta-analysis guidelines. Statistical analysis was performed using the Review Manager 5.3. The dichotomous data for the pedicle violation rate was summarized using relative risk (RR) and 95% confidence intervals (CIs) with the fixed-effects model. The level of significance was set at p < 0.05.
For this meta-analysis, seven studies used a total of 579 patients and 2981 screws. The results revealed that the accuracy of intraoperative data set acquisition method is significantly higher than preoperative one using 2 mm grading criteria (RR: 1.82, 95% CI: 1.09, 3.04, I = 0%, p = 0.02). However, there was no significant difference between two kinds of methods at the 0 mm grading criteria (RR: 1.13, 95% CI: 0.88, 1.46, I = 17%, p = 0.34). Using the 2-mm grading criteria, there was a higher accuracy of pedicle screw insertion in O-arm-assisted navigation than CT-based navigation method (RR: 1.96, 95% CI: 1.05, 3.64, I = 0%, p = 0.03). The accuracy between CT-based navigation and two-dimensional-based navigation showed no significant difference (RR: 1.02, 95% CI: 0.35-3.03, I = 0%, p = 0.97).
The intraoperative data set acquisition method may decrease the incidence of perforated screws over 2 mm but not increase the number of screws fully contained within the pedicle compared to preoperative CT-based navigation system. A significantly higher accuracy of intraoperative (O-arm) than preoperative CT-based navigation was revealed using 2 mm grading criteria.
比较基于术前计算机断层扫描(CT)与术中采集数据集用于脊柱导航系统时椎弓根螺钉置入的准确性。
系统检索PubMed(MEDLINE)、EMBASE和Web of Science截至2015年9月发表的文献。本综述遵循系统评价和Meta分析的首选报告项目指南。使用Review Manager 5.3进行统计分析。采用固定效应模型,用相对危险度(RR)和95%置信区间(CI)总结椎弓根侵犯率的二分数据。显著性水平设定为p<0.05。
对于本Meta分析,7项研究共纳入579例患者和2981枚螺钉。结果显示,使用2mm分级标准时,术中采集数据集方法的准确性显著高于术前方法(RR:1.82,95%CI:1.09,3.04,I² = 0%,p = 0.02)。然而,在0mm分级标准下,两种方法之间无显著差异(RR:1.13,95%CI:0.88,1.46,I² = 17%,p = 0.34)。采用2mm分级标准时,O型臂辅助导航下椎弓根螺钉置入的准确性高于基于CT的导航方法(RR:1.96,95%CI:1.05,3.64,I² = 0%,p = 0.03)。基于CT的导航与基于二维的导航之间的准确性无显著差异(RR:1.02,95%CI:0.35 - 3.03,I² = 0%,p = 0.97)。
与术前基于CT的导航系统相比,术中采集数据集方法可能会降低超过2mm的螺钉穿孔发生率,但不会增加完全位于椎弓根内的螺钉数量。采用2mm分级标准时,术中(O型臂)导航的准确性显著高于术前基于CT的导航。