Cubilla Michelle P, Santos Leonilda C, de Moraes Wanderlei, Cubas Zalmir S, Leutenegger Christian M, Estrada Marko, Vieira Rafael F C, Soares Maurilio J, Lindsay LeAnn L, Sykes Jane E, Biondo Alexander W
Department of Cell and Molecular Biology, Universidade Federal do Parana, Av. Cel. Francisco H. dos Santos, s/n., Curitiba, PR 81531-980, Brazil; Bela Vista Biological Sanctuary, Itaipu Binacional, R. Teresina, 62, Foz do Iguacu, PR 85866-900, Brazil.
Department of Veterinary Medicine, Universidade Federal do Parana, R. dos Funcionarios, 1540, Curitiba, PR 80035-050, Brazil.
Comp Immunol Microbiol Infect Dis. 2017 Jun;52:6-13. doi: 10.1016/j.cimid.2017.05.002. Epub 2017 May 12.
Hemoplasmas, the erythrocyte-associated mycoplasmas, have been detected in several primates, causing mostly subclinical infection. This study aimed to determine the prevalence of hemoplasma infection in captive and free-ranging monkeys from southern Brazil, as well as factors and hematological abnormalities associated with infection. Blood samples from 40 non-human primates (NHP) were tested for hemoplasmas and coinfections. An overall of 10/40 (25.0%) NHP tested positive for hemoplasmas using PCR-based assays, including 9/14 (64.3%) black howler monkeys (Alouatta caraya) and 1/24 (4.2%) black-horned capuchin (Sapajus nigritus). Infection was not statistically associated with anemia, but wild-born monkeys and male black howler monkeys were more likely to be positive when compared with captive-born animals and female black howler monkeys, respectively. The sequences from the black howler monkey hemoplasma were similar (94% identity) to the squirrel monkey hemoplasma ("Candidatus Mycoplasma kahanei") and were phylogenetically located in a different cluster when compared to the human hemoplasma ("Candidatus Mycoplasma haemohominis").
血支原体，即与红细胞相关的支原体，已在多种灵长类动物中被检测到，大多引起亚临床感染。本研究旨在确定巴西南部圈养和野生猴子中血支原体感染的患病率，以及与感染相关的因素和血液学异常。对40只非人灵长类动物（NHP）的血样进行了血支原体和合并感染检测。使用基于PCR的检测方法，总共10/40（25.0%）的NHP血支原体检测呈阳性，其中包括9/14（64.3%）的黑吼猴（Alouatta caraya）和1/24（4.2%）的黑角卷尾猴（Sapajus nigritus）。感染与贫血无统计学关联，但野生出生的猴子和雄性黑吼猴分别比圈养出生的动物和雌性黑吼猴更易呈阳性。黑吼猴血支原体的序列与松鼠猴血支原体（“卡氏支原体卡哈内菌”）相似（同一性为94%），与人类血支原体（“卡氏支原体人血菌”）相比，在系统发育上位于不同的簇中。
