Department of Psychiatry and Behavioral Medicine, Wake Forest School of Medicine, Winston-Salem, NC.
Department of Social Sciences and Health Policy, Wake Forest School of Medicine, Winston-Salem, NC.
Am J Geriatr Psychiatry. 2017 Nov;25(11):1249-1257. doi: 10.1016/j.jagp.2017.05.013. Epub 2017 May 26.
To examine the long-term effects of telephone-delivered cognitive-behavioral therapy (CBT-T) compared with nondirective supportive therapy (NST-T) in rural older adults with generalized anxiety disorder (GAD).
141 adults aged 60 years and older with a principal/co-principal diagnosis of GAD were randomized to either CBT-T or NST-T. CBT-T consisted of up to 11 sessions (9 were required) focused on recognition of anxiety symptoms, relaxation, cognitive restructuring and use of coping statements, problem-solving, worry control, behavioral activation, exposure therapy, and relapse prevention, with optional chapters on sleep and pain. NST-T consisted of 10 sessions focused on providing a supportive atmosphere in which participants could share and discuss their feelings and did not provide any direct suggestions. Primary outcomes included interviewer-rated anxiety severity and self-report worry severity measured at 9 months and 15 months after randomization. Mood-specific secondary outcomes included self-report GAD symptoms and depressive symptoms.
At 15 months, after adjustment for multiple testing, there was a significantly greater decline in general anxiety symptoms (difference in improvement: 3.31; 95% CI: 0.45-6.17; t = 2.29; df = 136; p = 0.024) and worry (difference in improvement: 3.13; 95% CI: 0.59-5.68; t = 2.43; df = 136; p = 0.016) among participants in CBT-T compared with those in the NST-T group. There were no significant differences between the conditions in terms of depressive symptoms (difference in improvement: 2.88; 95% CI: 0.17-5.60; t = 2.10; df = 136; p = 0.0376) and GAD symptoms (difference in improvement: 1.65; 95% CI: -0.20 to 3.50; t = 1.76; df = 136; p = 0.080).
CBT-T is superior to NST-T in reducing worry and anxiety symptoms 1 year after completing treatment.
研究电话传递认知行为疗法(CBT-T)与非指导性支持疗法(NST-T)对农村老年广泛性焦虑症(GAD)患者的长期疗效。
141 名年龄在 60 岁及以上、主要/共同诊断为 GAD 的成年人被随机分为 CBT-T 或 NST-T 组。CBT-T 包括最多 11 节(需完成 9 节)课程,重点关注识别焦虑症状、放松、认知重构和使用应对陈述、解决问题、控制担忧、行为激活、暴露疗法和预防复发,可选章节包括睡眠和疼痛。NST-T 由 10 节组成,重点是提供一个支持性的氛围,让参与者可以分享和讨论他们的感受,并且不会提供任何直接的建议。主要结局指标包括 9 个月和 15 个月后随机分组时的访谈者评定的焦虑严重程度和自我报告的担忧严重程度。情绪特异性次要结局指标包括自我报告的 GAD 症状和抑郁症状。
在经过多次检验调整后,在 15 个月时,CBT-T 组的一般焦虑症状(改善差异:3.31;95%置信区间:0.45-6.17;t=2.29;df=136;p=0.024)和担忧(改善差异:3.13;95%置信区间:0.59-5.68;t=2.43;df=136;p=0.016)显著下降,而 NST-T 组则没有显著差异。在抑郁症状(改善差异:2.88;95%置信区间:0.17-5.60;t=2.10;df=136;p=0.0376)和 GAD 症状(改善差异:1.65;95%置信区间:-0.20 至 3.50;t=1.76;df=136;p=0.080)方面,两种治疗方式也没有显著差异。
在完成治疗 1 年后,CBT-T 比 NST-T 更能降低担忧和焦虑症状。