Treasure J L, Gordon P A, King E A, Wheeler M, Russell G F
Lancet. 1985;2(8469-70):1379-82. doi: 10.1016/s0140-6736(85)92553-x.
The ultrasonographic appearance of ovaries and uterus during weight-gain in patients with anorexia nervosa is described. In 11 patients who had sequential scans, ovarian volume on admission was considerably smaller than that of normal women but increased logarithmically with weight-gain. When body mass index (BMI) reached 17 kg/m2, ovaries were shown to contain multiple small cysts in all cases. In 5 patients further weight-gain led to the appearance of a dominant cyst; average BMI was approximately 19 kg/m2 at this stage. The changes in ovarian morphology resembled those of normal pubertal development. These results lend support to the suggestion that hypothalamic-gonadal axis dysfunction in anorexia nervosa is a concomitant of starvation; in the management of infertility, an ultrasonographic appearance of cystic ovaries should alert the clinician to the likelihood of undernutrition as the primary disorder in need of treatment.
描述了神经性厌食症患者体重增加期间卵巢和子宫的超声表现。在11例接受连续扫描的患者中，入院时卵巢体积明显小于正常女性，但随体重增加呈对数增加。当体重指数（BMI）达到17kg/m²时，所有病例的卵巢均显示含有多个小囊肿。在5例患者中，进一步体重增加导致出现优势囊肿；此时平均BMI约为19kg/m²。卵巢形态的变化类似于正常青春期发育。这些结果支持了以下观点，即神经性厌食症中的下丘脑-性腺轴功能障碍是饥饿的伴随症状；在不孕症管理中，卵巢囊性的超声表现应提醒临床医生注意营养不良作为需要治疗的主要疾病的可能性。
