Trabelsi Iteb, Essid Kamel, Frikha Mohamed Hedi
Laboratory of Physical and Organic Chemistry: Department of Chemistry, Faculty of Sciences in Sfax.
J Oleo Sci. 2017;66(7):667-676. doi: 10.5650/jos.ess17008.
The article deals with the use of mixed anhydrides for the synthesis of fatty esters. Both aliphatic and aromatic acids are involved, indicating different behaviors according to the chain length of the aliphatic acid. We describe a novel and efficient method for the synthesis of fatty esters by the esterification reaction of primary, secondary and tertiary alcohols with mixed carboxylic-palmitic anhydrides using resin Amberlyst-15 as heterogeneous acid catalyst. Influence of various reaction parameters such as molar ratio (anhydride/alcohol), catalyst amount, type of alcohol and type of mixed anhydride were studied to optimize the conditions for maximum yield. Among tested anhydrides we quote mainly the 4-chlorobenzoic palmitic anhydride because it was both reactive and selective for the preparation of palmitic acid ester. This anhydride gave a good yield of palmitic ester.
本文论述了混合酸酐在脂肪酸酯合成中的应用。其中涉及脂肪族酸和芳香族酸，这表明根据脂肪族酸的链长会有不同的反应行为。我们描述了一种新颖且高效的方法，即使用树脂Amberlyst - 15作为非均相酸催化剂，通过伯醇、仲醇和叔醇与混合羧酸 - 棕榈酸酐的酯化反应来合成脂肪酸酯。研究了各种反应参数，如摩尔比（酸酐/醇）、催化剂用量、醇的类型和混合酸酐的类型，以优化条件实现最大产率。在测试的酸酐中，我们主要提及4 - 氯苯甲酸棕榈酸酐，因为它在制备棕榈酸酯时既具有反应活性又具有选择性。这种酸酐能得到较高产率的棕榈酸酯。
