远程控制 BBB：外泌体和 microRNA 的故事。
Remote control of BBB: A tale of exosomes and microRNA.
机构信息
Zilkha Neurogenetic Institute and Department of Physiology and Neuroscience, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.
出版信息
Cell Res. 2017 Jul;27(7):849-850. doi: 10.1038/cr.2017.71. Epub 2017 May 19.
Abstract
Exosome-mediated intercellular communication has become an emerging field of human health and diseases. A recent study published by Cell Research reports that in zebrafish neurons can remotely regulate blood-brain barrier integrity by delivering miR-132 through secretion of exosomes.
摘要
外泌体介导的细胞间通讯已成为人类健康和疾病领域的一个新兴研究方向。最近《细胞研究》杂志上发表的一项研究表明，在斑马鱼神经元中，可通过外泌体分泌 miR-132 来远程调节血脑屏障的完整性。
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