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小儿耳源性破伤风:尼日利亚免疫接种不力的一个证据。

Paediatric otogenic tetanus: an evidence of poor immunization in Nigeria.

作者信息

Ogunkeyede Segun Ayodeji, Daniel Adekunle, Ogundoyin Omowonuola

机构信息

Department of Otorhinolaryngology, College of Medicine, University of Ibadan, Ibadan and University College Hospital, Ibadan Nigeria.

出版信息

Pan Afr Med J. 2017 Mar 29;26:177. doi: 10.11604/pamj.2017.26.177.11519. eCollection 2017.

Abstract

Suppurative otitis media is a common childhood infection that predisposes to otogenic tetanus. Tetanus is a vaccine preventable disease that is associated with high cost of care and mortality. This study highlights reasons for otogenic tetanus in Nigerian children and way of reducing the menace. This is a 5-year retrospective review of all patients managed for otogenic tetanus in at the Department of Otorhinolaryngology, University College Hospital, Ibadan. The data collected include demographic, clinical presentations, tetanus immunisation history, and duration of hospital admission, and management- outcome. There were 23 patients comprising of 13(56.5 %) males and 10 (43.5%) females, male to female ratio was 1.3:1. The age ranged between 11 months and12 years (mean age 3.4 years ± 2.1). All the patients presented with discharging ear, trismus and spasms. The onset of symptoms prior hospital presentation ranged between 2 - 11 days (mean 3.0 days ± 1.3). Only 12(52.1%) patients had complete childhood tetanus immunisation, 6(26.1) % had no tetanus immunisation and no other childhood immunisation, while 5(21.7%) had partial tetanus immunisation. The discharging ears were managed by self-medication and other harmful health practices. The hospital admission ranged from 20 days - 41days (average of 23days) and there were 3(13.0 %) death. Tetanus immunization was not received because of; non- availability of the vaccine at health centers, lack of health facility in communities, fear of complications from immunization, poor awareness of the immunization programme. Tetanus, an immunisable disease, is still a major problem in Nigeria.

摘要

化脓性中耳炎是一种常见的儿童感染性疾病,易引发耳源性破伤风。破伤风是一种可通过疫苗预防的疾病,其治疗成本高昂且死亡率高。本研究强调了尼日利亚儿童耳源性破伤风的发病原因及减少这一威胁的方法。这是对伊巴丹大学学院医院耳鼻喉科收治的所有耳源性破伤风患者进行的一项为期5年的回顾性研究。收集的数据包括人口统计学信息、临床表现、破伤风免疫史、住院时间以及治疗结果。共有23例患者,其中男性13例(56.5%),女性10例(43.5%),男女比例为1.3:1。年龄范围在11个月至12岁之间(平均年龄3.4岁±2.1岁)。所有患者均有耳部流脓、牙关紧闭和痉挛症状。入院前症状出现时间为2至11天(平均3.0天±1.3天)。仅有12例(52.1%)患者完成了儿童期破伤风免疫接种,6例(26.1%)未接种破伤风疫苗且未进行其他儿童期免疫接种,5例(21.7%)进行了部分破伤风免疫接种。耳部流脓通过自我用药及其他有害健康的做法进行处理。住院时间为20天至41天(平均23天),有3例(13.0%)死亡。未接种破伤风疫苗的原因包括:健康中心无疫苗、社区缺乏卫生设施、担心免疫接种并发症、对免疫接种计划的认知不足。破伤风作为一种可免疫预防的疾病,在尼日利亚仍然是一个主要问题。

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