Shah-Becker Shivani, Pennock Michael, Sinoway Lawrence, Goldenberg David, Goyal Neerav
Division of Otolaryngology - Head and Neck Surgery, Department of Surgery, The Pennsylvania State University, College of Medicine, Hershey, Pennsylvania.
The Pennsylvania State University, College of Medicine, Hershey, Pennsylvania.
Head Neck. 2017 Oct;39(10):2135-2141. doi: 10.1002/hed.24857. Epub 2017 Jul 4.
Baroreceptor dysfunction and reflex failure may occur after surgery affecting the carotid artery. The implications for patients undergoing treatment for head and neck cancer are not well described.
A literature search of PubMed was performed between March 2016 and May 2016. Search terms used individually and in combination included: "baroreflex failure," "carotid sinus sensitivity," "carotid endarterectomy," "carotid body tumor," and "head and neck cancer." Bibliographies of included articles were also reviewed for additional pertinent articles.
There is evidence of baroreceptor failure in certain patients after interventions associated with the carotid artery, including carotid endarterectomy and carotid body tumor excision. Few studies have been performed investigating the potential effect of head and neck surgery treatment, including surgery and/or radiation, on baroreflex function.
Head and neck cancer treatment has the potential to cause baroreflex failure, and this is likely an underrecognized and underdiagnosed condition.
影响颈动脉的手术后可能会出现压力感受器功能障碍和反射衰竭。对于接受头颈癌治疗的患者，其影响尚未得到充分描述。
于2016年3月至2016年5月对PubMed进行文献检索。单独使用及组合使用的检索词包括：“压力反射衰竭”、“颈动脉窦敏感性”、“颈动脉内膜切除术”、“颈动脉体瘤”及“头颈癌”。还对纳入文章的参考文献进行了审查以查找其他相关文章。
有证据表明，在与颈动脉相关的干预措施（包括颈动脉内膜切除术和颈动脉体瘤切除术）后，部分患者会出现压力感受器衰竭。很少有研究调查头颈外科治疗（包括手术和/或放疗）对压力反射功能的潜在影响。
头颈癌治疗有可能导致压力反射衰竭，而这可能是一种未得到充分认识和诊断的疾病。
