在淋巴系统恶性肿瘤患者中检测猿猴C型病毒和人类逆转录病毒HTLV的主要核心蛋白及其抗体。
Detection of main core proteins of simian C-type viruses and human retrovirus HTLV and antibodies to them in patients with lymphoid malignancies.
作者信息
Tóth F D, Váczi L, Szabó B, Kiss J, Réthy A, Kiss A, Telek B, Kovács I, Kiss C, Rák K
出版信息
Acta Microbiol Hung. 1985;32(3):267-73.
Peripheral leukocytes or lymph node cells and blood plasma samples from patients with lymphoid malignancies were investigated for immunological markers of BaEV, GaLV and HTLV. Antigens and antibodies were shown with radioimmunoassay. Antigen related to the p30 core protein of BaEV could be detected in each cell type of leukaemias and lymphomas. Antigen related to the GaLV p30 was found mainly in B- and O-cell forms, while that related to the p24 protein of HTLV could be detected only in two T-cell malignancies. Antibodies reactive with these antigens showed a similar distribution.
对淋巴系统恶性肿瘤患者的外周血白细胞或淋巴结细胞以及血浆样本进行了调查，以检测巴贝斯白血病病毒（BaEV）、猫白血病病毒（GaLV）和人类嗜T淋巴细胞病毒（HTLV）的免疫标记物。采用放射免疫测定法检测抗原和抗体。与BaEV的p30核心蛋白相关的抗原在白血病和淋巴瘤的每种细胞类型中均可检测到。与GaLV p30相关的抗原主要存在于B细胞和O细胞形式中，而与HTLV p24蛋白相关的抗原仅在两种T细胞恶性肿瘤中可检测到。与这些抗原发生反应的抗体显示出相似的分布。
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