Wolkowitz O M, Pickar D, Doran A R, Breier A, Tarell J, Paul S M
Am J Psychiatry. 1986 Jan;143(1):85-7. doi: 10.1176/ajp.143.1.85.
Alprazolam, when added under double-blind conditions to a stable neuroleptic regimen in two patients with schizophrenia, resulted in clinically apparent improvement in positive and negative schizophrenic symptoms. Both patients showed significant worsening of symptoms following reduction or discontinuation of alprazolam.
在双盲条件下，向两名精神分裂症患者稳定的抗精神病药物治疗方案中添加阿普唑仑后，阳性和阴性精神分裂症症状在临床上有明显改善。在减少或停用阿普唑仑后，两名患者的症状均显著恶化。
