Pecknold J C
Douglas Hospital Research Centre, Verdun, Quebec, Canada.
J Psychiatry Neurosci. 1993 Mar;18(2):82-4.
A retrospective survey of the use of benzodiazepines by 149 outpatients with schizophrenia found that 59% were on neuroleptics alone and 41% were receiving both neuroleptics and benzodiazepines. Of the group receiving both, 64% were taking a benzodiazepine as a hypnotic agent; 23% of those were taking alprazolam as an anxiolytic. The patients taking neuroleptics and alprazolam required significantly less neuroleptic medication than the group receiving neuroleptics alone.
一项对149名精神分裂症门诊患者使用苯二氮䓬类药物情况的回顾性调查发现,59%的患者仅服用抗精神病药物,41%的患者同时服用抗精神病药物和苯二氮䓬类药物。在同时服用这两种药物的患者中,64%将苯二氮䓬类药物作为催眠剂使用;其中23%的患者服用阿普唑仑来缓解焦虑。与仅服用抗精神病药物的组相比,同时服用抗精神病药物和阿普唑仑的患者所需的抗精神病药物明显更少。