Mohammadi Seyed-Farzad, Mohammadzadeh Vahid, Kadivar Sakineh, Beheshtnejad Amir-Houshang, Norooznezhad Amir Hossein, Hashemi Seyed-Hassan
Eye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Qazvin Square, P.O. Box 1336616351, Tehran, Iran.
Eye Research Center, Amiralmomenin Eye Hospital, Guilan University of Medical Sciences, Rasht, Iran.
Int Ophthalmol. 2018 Aug;38(4):1611-1619. doi: 10.1007/s10792-017-0631-2. Epub 2017 Jul 4.
The term 'keratoconus (KC) suspect' is used as a blanket term to refer to any deviation of virgin cornea shape toward KC features. We intend to subclassify such topographies in meaningful and informative designations.
Pentacam corneal topographies of 199 consecutive refractive surgery candidates (398 eyes) are examined. Features of steepness, inferior-superior asymmetry, focal steepening, thinning, and bounded anterior or posterior elevations are observed in the quad map. Scissoring on retinoscopy, loss of best spectacle-corrected visual acuity, and iron ring deposition were looked for. Through iterative observation and refinement of classification criteria-partly taken from the literature-all eyes were designated a specific topographic diagnosis, i.e., circumventing the usage of the expression KC 'suspect'.
Topographies of 308, 48, 21, 13, 6, 1, and 1 (collectively 398 eyes) were designated: normal, 'atypical normal,' forme fruste KC, posterior KC, subclinical/mild KC, superior KC, and pseudo-KC, respectively.
Current imaging modalities of the cornea and our accumulated experience in refractive science allow assignment of distinctive designations for abnormal corneal shapes along the topography spectrum. We devised and used the expressions: normal, atypical normal, forme fruste (arrested-incomplete) KC, posterior KC, subclinical (active latent) KC, superior KC, and pseudo-keratoconus. Identification of 1.5% (mild) KC highlights the importance of screening for ultraviolet cross-linkage candidacy in refractive surgery referrals.
术语“圆锥角膜(KC)疑似病例”用作统称,指原始角膜形状向KC特征的任何偏差。我们打算将此类地形图进行有意义且信息丰富的分类。
检查了199例连续的屈光手术候选者(398只眼)的Pentacam角膜地形图。在四象限图中观察陡峭度、上下不对称性、局限性陡峭、变薄以及局限性前或后隆起等特征。查找检影时的剪刀征、最佳眼镜矫正视力下降以及铁环沉积。通过反复观察并完善分类标准(部分取自文献),所有眼睛都被指定了特定的地形图诊断,即避免使用“疑似”KC这一表述。
308只、48只、21只、13只、6只、1只和1只(共398只眼)的地形图分别被指定为:正常、“非典型正常”、顿挫型KC、后圆锥角膜、亚临床/轻度KC、上圆锥角膜和假性圆锥角膜。
当前的角膜成像模式以及我们在屈光科学方面积累的经验,使得能够沿着地形图谱为异常角膜形状指定独特的名称。我们设计并使用了以下表述:正常、非典型正常、顿挫型(停滞-不完全型)KC、后圆锥角膜、亚临床(活跃潜伏型)KC、上圆锥角膜和假性圆锥角膜。1.5%(轻度)KC的识别凸显了在屈光手术转诊中筛查紫外线交联候选资格的重要性。