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医学中的利益冲突:认真对待多样性。

Conflicts of interest in medicine: taking diversity seriously.

作者信息

Williams Jane, Mayes Christopher, Komesaroff Paul, Kerridge Ian, Lipworth Wendy

机构信息

Centre for Values, Ethics and the Law in Medicine (VELiM), University of Sydney, Sydney, New South Wales, Australia.

Faculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, Victoria, Australia.

出版信息

Intern Med J. 2017 Jul;47(7):739-746. doi: 10.1111/imj.13471.

Abstract

Conflicts of interest (COI) are considered ubiquitous in many healthcare arrangements, but there is disagreement on how COI should be defined, whether non-financial conflicts deserve attention and the relationship between COI and harm. We conducted a study of Australian healthcare professionals and students to gain a better understanding of the way that COI are understood in practice. In this paper, we outline an empirically derived taxonomy of the understanding of, and attitudes towards, COI. We carried out 25 semistructured interviews with clinicians working in several fields across Australia and held six focus group discussions with medical students in New South Wales. Interviewees and focus groups followed similar question routes investigating participants' understanding of COI and views of management. All data were compared and analysed using a matrix of pre-determined questions. There were, broadly, two views of COI: that COI were potentially harmful and morally compromising and another that saw COI as less serious and easily managed through existing structures. Definitions of COI varied widely and were both financial and non-financial. Causes of COI were, variously, systemic, individual and/or relational. Some participants associated COI with moral wrongdoing, and a variety of potential harms was identified. Views on how COI should be managed were similarly varied. We found considerable heterogeneity in how COI are understood in practice. This has implications for management systems that are currently in place, and we suggest a more sophisticated system for considering and mitigating COI.

摘要

利益冲突(COI)在许多医疗保健安排中被认为普遍存在,但对于如何定义利益冲突、非财务冲突是否值得关注以及利益冲突与危害之间的关系存在分歧。我们对澳大利亚的医疗保健专业人员和学生进行了一项研究,以更好地了解在实践中人们对利益冲突的理解方式。在本文中,我们概述了一种基于实证得出的对利益冲突的理解和态度的分类法。我们对澳大利亚多个领域的临床医生进行了25次半结构化访谈,并与新南威尔士州的医学生进行了6次焦点小组讨论。受访者和焦点小组遵循类似的问题路径,调查参与者对利益冲突的理解以及管理观点。所有数据都使用预先确定的问题矩阵进行比较和分析。大致上,对利益冲突有两种观点:一种认为利益冲突具有潜在危害且在道德上存在问题,另一种则认为利益冲突不太严重且可通过现有结构轻松管理。利益冲突的定义差异很大,包括财务和非财务方面。利益冲突的原因各不相同,有系统性的、个人的和/或关系性的。一些参与者将利益冲突与道德不当行为联系起来,并识别出了各种潜在危害。关于如何管理利益冲突的观点同样各不相同。我们发现在实践中对利益冲突的理解存在相当大的异质性。这对当前的管理系统有影响,我们建议建立一个更复杂的系统来考虑和减轻利益冲突。

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