School of Instrument Science and Opto-Electronics Engineering, Hefei University of Technology, Hefei 230009, China.
Institute of Biomedical Technologies, Auckland University of Technology, Auckland 1142, New Zealand.
Sensors (Basel). 2017 Jul 5;17(7):1572. doi: 10.3390/s17071572.
Early-stage cancer detection could reduce breast cancer death rates significantly in the long-term. The most critical point for best prognosis is to identify early-stage cancer cells. Investigators have studied many breast diagnostic approaches, including mammography, magnetic resonance imaging, ultrasound, computerized tomography, positron emission tomography and biopsy. However, these techniques have some limitations such as being expensive, time consuming and not suitable for young women. Developing a high-sensitive and rapid early-stage breast cancer diagnostic method is urgent. In recent years, investigators have paid their attention in the development of biosensors to detect breast cancer using different biomarkers. Apart from biosensors and biomarkers, microwave imaging techniques have also been intensely studied as a promising diagnostic tool for rapid and cost-effective early-stage breast cancer detection. This paper aims to provide an overview on recent important achievements in breast screening methods (particularly on microwave imaging) and breast biomarkers along with biosensors for rapidly diagnosing breast cancer.
早期癌症检测可以从长远来看显著降低乳腺癌死亡率。最佳预后的最关键一点是识别早期癌细胞。研究人员已经研究了许多乳腺诊断方法,包括乳房 X 线摄影术、磁共振成像、超声、计算机断层扫描、正电子发射断层扫描和活组织检查。然而,这些技术存在一些局限性,例如昂贵、耗时且不适合年轻女性。开发高灵敏度和快速的早期乳腺癌诊断方法迫在眉睫。近年来,研究人员已经关注于开发生物传感器,使用不同的生物标志物来检测乳腺癌。除了生物传感器和生物标志物外,微波成象技术也被作为一种快速、经济有效的早期乳腺癌检测的有前途的诊断工具进行了深入研究。本文旨在综述最近在乳腺筛查方法(特别是微波成象)和乳腺生物标志物以及生物传感器方面的重要进展,用于快速诊断乳腺癌。