Sadashiva Nishanth, Nandeesh Bevinahalli N, Shukla Dhaval, Devi Bhagavatula I
Department of Neurosurgery, National Institute of Mental Health and Neurosciences, Bengaluru, India.
Neurosciences (Riyadh). 2017 Jul;22(3):216-219. doi: 10.17712/nsj.2017.3.20160465.
Ventricular involvement in central nervous system tuberculosis can be in the form of tuberculous ependymitis, intraventricular tuberculoma, intraventricular tuberculous abscess, choroid plexitis and choroid plexus tuberculoma. Only a few cases of choroid plexus tuberculomas have been described and even more rare is the description of the role of endoscopy in management of intraventricular tuberculomas. We report a 33-year-old patient while on treatment for tubercular meningitis who developed a left side choroid plexus lesion with loculated temporal horn. To confirm the diagnosis, endoscopic biopsy of the lesion was carried out. The final histopathology was tuberculoma. Intraventricular tuberculomas are usually associated with recalcitrant lesions, probably due to the poor drug levels within the CSF or as an indirect effect of immune resistance and biopsy becomes important to rule out other possibilities.
中枢神经系统结核的脑室受累可表现为结核性室管膜炎、脑室内结核瘤、脑室内结核脓肿、脉络丛炎和脉络丛结核瘤。仅有少数脉络丛结核瘤的病例被描述过,而关于内镜在脑室内结核瘤治疗中的作用的描述更为罕见。我们报告一名33岁正在接受结核性脑膜炎治疗的患者,其左侧脉络丛出现病变并伴有颞角分隔。为明确诊断,对该病变进行了内镜活检。最终组织病理学检查结果为结核瘤。脑室内结核瘤通常与难治性病变相关,这可能是由于脑脊液中药物浓度低,或者是免疫抵抗的间接作用,而活检对于排除其他可能性很重要。