Hsu P W, Lin T K, Chang C N
First Division of Neurosurgery, Department of Surgery, Chang Gung Memorial Hospital, Kwei-Shan, Taoyuan, Taiwan.
Acta Neurochir (Wien). 2004 Oct;146(10):1151-3; discussion 1153-4. doi: 10.1007/s00701-004-0291-7.
Intracranial tuberculoma is typically located in the parenchyma. Lesions limited to the ventricular system are uncommon. It is difficult to make a differential diagnosis from other lesions if no systemic tuberculosis is present. This study investigates a case of solitary intraventricular tuberculoma in a 19-year-old female patient with an initial clinical symptom of progressive headache. Cranial computed tomography revealed a strongly enhanced lesion in the lateral ventricle. Histopathology of the tumor demonstrated chronic inflammation, caseous necrosis, epithelioid cells and Langhans' giant cell. The culture study grew M. Tuberculosis. Solitary intraventricular tuberculoma in adults is extremely rare. Medical treatment is the preferred management method of this disease, and surgical intervention should be considered in certain situations.
颅内结核瘤通常位于脑实质内。局限于脑室系统的病变并不常见。如果没有全身性结核病，很难与其他病变进行鉴别诊断。本研究调查了一名19岁女性患者的孤立性脑室内结核瘤病例，其初始临床症状为进行性头痛。头颅计算机断层扫描显示侧脑室内有一个强化明显的病变。肿瘤的组织病理学表现为慢性炎症、干酪样坏死、上皮样细胞和朗汉斯巨细胞。培养研究培养出结核分枝杆菌。成人孤立性脑室内结核瘤极为罕见。药物治疗是本病的首选治疗方法，在某些情况下应考虑手术干预。
