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Zika 病毒感染:巴黎旅行中心首例输入性病例报告。

Zika virus infection: report of the first imported cases in a Paris travel centre.

机构信息

Service des Maladies Infectieuses et Tropicales, AP-HP, Hôpital Bichat, Hôpitaux Paris Nord Val de Seine, Paris, France.

INSERM, Infections, Antimicrobiens, Modélisation, Evolution (IAME), UMR 1137, Paris, France.

出版信息

J Travel Med. 2016 Jul 1;24(1). doi: 10.1093/jtm/taw066.

DOI:10.1093/jtm/taw066
PMID:28679155
Abstract

We describe characteristics of 17 patients with a Zika virus (ZIKV) infection seen in a Travel Center in Paris during the 4 months following the WHO alert on ZIKV. Sixteen were imported cases, including 13 from the Caribbean. One was a women living in Paris infected through sexual transmission. One case was a pregnant woman. All cases were symptomatic with fever, fatigue and cutaneous rash in 15/17, 13/17, and 16/17, respectively. Leucopenia was observed in 6/17, thrombopenia in 2/17. Diagnosis was confirmed by ZIKV RT-PCR (plasma: 12/17; urine 15/17) or detection of ZIKV IgM (2/17). Two patients were hospitalized but all evolved well.

摘要

我们描述了在世界卫生组织发出寨卡病毒警报后的 4 个月内,在巴黎旅行中心就诊的 17 例寨卡病毒(ZIKV)感染患者的特征。16 例为输入性病例,其中 13 例来自加勒比地区。1 例为居住在巴黎的女性,通过性传播感染。1 例为孕妇。所有病例均有发热、疲劳和皮疹,分别为 15/17、13/17 和 16/17,17 例中有 6 例出现白细胞减少症,2 例出现血小板减少症。通过 ZIKV RT-PCR(血浆:12/17;尿液 15/17)或检测 ZIKV IgM(2/17)确诊。2 例患者住院治疗,但均恢复良好。

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