Leisman Staci, Burkhoff Daniel
Department of Medicine and Medical Education, Icahn School of Medicine at Mount Sinai, New York, New York; and
Cardiovascular Research Foundation and Columbia University Division of Cardiology, New York, New York.
Adv Physiol Educ. 2017 Sep 1;41(3):415-424. doi: 10.1152/advan.00204.2016.
The purpose of this laboratory exercise is to model the changes in preload, afterload, and contractility on a simulated pressure-volume loop and to correlate those findings with common measurements of clinical cardiovascular physiology. Once students have modeled these changes on a healthy heart, the students are asked to look at a simulated case of cardiogenic shock. Effects on preload, contractility, and afterload are explored, as well as the hemodynamic effects of a number of student-suggested treatment strategies.
本实验的目的是在模拟压力-容积环上模拟前负荷、后负荷和心肌收缩力的变化，并将这些结果与临床心血管生理学的常见测量结果相关联。一旦学生在健康心脏上模拟了这些变化，就要求他们观察一个心源性休克的模拟病例。探讨对前负荷、心肌收缩力和后负荷的影响，以及一些学生提出的治疗策略的血流动力学效应。
