Julius Bernstein Institute of Physiology, University of Halle, Halle/Saale, Germany.
Adv Physiol Educ. 2020 Sep 1;44(3):423-429. doi: 10.1152/advan.00069.2020.
Functional understanding of the different parts of the cardiovascular system is essential for an insight into pathomechanisms of numerous diseases. During training cardiovascular physiology, students and early-stage medical personnel should understand the role of different functional parameters for systolic and diastolic blood pressure, as well as for blood flow. The impact of isolated parameters can only be studied in models. Here physical hydraulic models are an advantage in which the students have a direct contact to the mechanical properties of the circulatory system. But these models are often difficult to handle. The aim of the present study was to develop a comprehensive model of the cardiovascular system, including a mechanical heart with valves, an elastic aorta, a more rigid peripheral artery system, a total peripheral resistance, and a venous reservoir representing the variable cardiac preload. This model allows one to vary systematically several functional parameters and to continuously record their impact on pressure and flow. This model is embedded into a computer-based teaching system (LabTutor) in which the students are guided through the handling of the model (as well as the systematic variation of parameters), and the measured data can be analyzed. This hybrid teaching system, which is routinely integrated in physiology laboratory courses of medical students, allows students to work with a complex hydraulic model of the cardiovascular system and to analyze systematically the impact of influencing variables (e.g., increased peripheral resistance or changed cardiac preload) as well as pathophysiological dysfunctions (e.g., reduced aortic compliance).
了解心血管系统的不同部分的功能对于深入了解许多疾病的病理机制至关重要。在心血管生理学培训中,学生和初级医务人员应该了解不同功能参数对收缩压和舒张压以及血流量的作用。孤立参数的影响只能在模型中研究。在这里,物理液压模型具有优势,学生可以直接接触到循环系统的机械特性。但这些模型通常难以操作。本研究的目的是开发一种综合的心血管系统模型,包括带瓣膜的机械心脏、弹性主动脉、刚性外周动脉系统、总外周阻力和代表可变心脏前负荷的静脉储液器。该模型允许系统地改变几个功能参数,并连续记录它们对压力和流量的影响。该模型被嵌入到基于计算机的教学系统(LabTutor)中,学生在该系统中可以通过模型的操作(以及参数的系统变化)来指导,并可以分析测量数据。这种混合教学系统已常规整合到医学生的生理学实验室课程中,使学生能够使用心血管系统的复杂液压模型,并系统地分析影响变量(例如,外周阻力增加或心脏前负荷改变)以及病理生理功能障碍(例如,主动脉顺应性降低)的影响。