Griffiths P D
J Hosp Infect. 1985 Dec;6 Suppl C:35-41. doi: 10.1016/s0195-6701(85)80007-4.
Several assays are in preparation for the diagnosis of cytomegalovirus infection in acquired immune deficiency syndrome and other immunocompromised patients. In particular, ELISA and DNA probes look to be particularly promising for testing body fluids and tissue sections respectively but these assays are not currently available. The technique of detection of early fluorescent antigen foci (DEAFF) has for some time been available as a diagnostic service to immunocompromised patients served by the author's laboratory. Although it requires cell culture and immunofluorescent techniques it is capable of detecting most patients with productive infection. In particular, the rapid availability of results has allowed patients to be entered into trials of new antiviral agents.
目前正在准备多种检测方法，用于诊断获得性免疫缺陷综合征及其他免疫功能低下患者的巨细胞病毒感染。特别是，酶联免疫吸附测定（ELISA）和DNA探针分别在检测体液和组织切片方面看起来特别有前景，但这些检测方法目前尚未可用。早期荧光抗原灶检测技术（DEAFF）在一段时间以来一直作为一种诊断服务，提供给作者所在实验室服务的免疫功能低下患者。尽管它需要细胞培养和免疫荧光技术，但它能够检测出大多数有活动性感染的患者。特别是，检测结果的快速可得性使得患者能够参与新抗病毒药物的试验。
