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产科出血的风险因素及管理的最新进展。

An update on the risk factors for and management of obstetric haemorrhage.

作者信息

Sebghati Mercede, Chandraharan Edwin

机构信息

St George's University Hospitals NHS Foundation Trust, London, UK.

出版信息

Womens Health (Lond). 2017 Aug;13(2):34-40. doi: 10.1177/1745505717716860. Epub 2017 Jul 6.

Abstract

Obstetric haemorrhage is associated with increased risk of serious maternal morbidity and mortality. Postpartum haemorrhage is the commonest form of obstetric haemorrhage, and worldwide, a woman dies due to massive postpartum haemorrhage approximately every 4 min. In addition, many experience serious morbidity such as multi-organ failure, complications of multiple blood transfusions, peripartum hysterectomy and unintended damage to pelvic organs, loss of fertility and psychological sequelae, including posttraumatic stress disorders. Anticipation of massive postpartum haemorrhage, prompt recognition of the cause and institution of timely and appropriate measures to control bleeding and replacement of the lost blood volume and restoration of oxygen carrying capacity (i.e. haemoglobin) and correction of the 'washout phenomenon' leading to coagulopathy will help save lives. Obstetric shock index may help in avoidance of underestimation of blood loss and the use of tranexamic acid, oxytocics and timely peripartum hysterectomy, if appropriate, will help save lives. Triple P procedure has been recently developed as the conservative surgical alternative for women with abnormal invasion of the placenta and has been shown to significantly reduce the blood loss and to reduce inpatient stay.

摘要

产科出血与孕产妇严重发病和死亡风险增加相关。产后出血是产科出血最常见的形式,在全球范围内,大约每4分钟就有一名妇女因大量产后出血死亡。此外,许多人会经历严重的发病情况,如多器官功能衰竭、多次输血的并发症、围产期子宫切除术以及盆腔器官意外损伤、生育能力丧失和心理后遗症,包括创伤后应激障碍。对大量产后出血进行预判、及时识别病因并采取及时适当的措施控制出血、补充丢失的血容量、恢复氧携带能力(即血红蛋白)以及纠正导致凝血障碍的“冲洗现象”,将有助于挽救生命。产科休克指数可能有助于避免低估失血量,而使用氨甲环酸、宫缩剂以及在适当情况下及时进行围产期子宫切除术,将有助于挽救生命。三联P手术最近已被开发出来,作为胎盘异常侵入妇女的保守手术替代方案,已被证明可显著减少失血量并缩短住院时间。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ee55/5557181/301a250a37dc/10.1177_1745505717716860-fig1.jpg

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