基于产房复苏方式和强度的新生儿结局
Neonatal outcomes based on mode and intensity of delivery room resuscitation.
作者信息
Bashir A, Bird B, Wu L, Welles S, Taylor H, Anday E, Bhandari V
机构信息
St George's University School of Medicine, St George's, Grenada.
Department of Pediatrics, Hahnemann University Hospital, Philadelphia, PA, USA.
出版信息
J Perinatol. 2017 Oct;37(10):1103-1107. doi: 10.1038/jp.2017.102. Epub 2017 Jul 6.
OBJECTIVE
To examine outcomes of neonates based on the mode and intensity of resuscitation received in the delivery room (DR).
STUDY DESIGN
A retrospective study of 439 infants with birth weight ⩽1500 g receiving DR resuscitation at two hospital centers in Philadelphia, Pennsylvania.
RESULTS
Of 439 infants, 22 (5%) received routine care, 188 (43%) received noninvasive positive pressure ventilation (PPV) and 229 (52%) received endotracheal tube (ETT) intubation in the DR. Adjusted odds for respiratory distress syndrome was associated with lower rates in infants requiring lower intensity of DR resuscitation (P<0.001). Noninvasive PPV vs ETT was associated with decreased odds of developing intraventricular hemorrhage and retinopathy of prematurity (P<0.05). Routine vs noninvasive PPV or ETT had decreased odds of developing bronchopulmonary dysplasia (P<0.05).
CONCLUSION
Decreased intensity of DR resuscitation was associated with a decreased risk of specific morbidities.
目的
根据产房（DR）复苏的方式和强度来研究新生儿的结局。
研究设计
对宾夕法尼亚州费城两个医院中心出生体重≤1500g且在产房接受复苏的439例婴儿进行回顾性研究。
结果
在439例婴儿中，22例（5%）接受常规护理，188例（43%）接受无创正压通气（PPV），229例（52%）在产房接受气管插管（ETT）。呼吸窘迫综合征的校正比值与产房复苏强度较低的婴儿发生率较低相关（P<0.001）。无创PPV与ETT相比，发生脑室内出血和早产儿视网膜病变的几率降低（P<0.05）。常规护理与无创PPV或ETT相比，发生支气管肺发育不良的几率降低（P<0.05）。
结论
产房复苏强度降低与特定疾病的风险降低相关。
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