文献检索文档翻译深度研究
Suppr Zotero 插件Zotero 插件
邀请有礼套餐&价格历史记录

新学期，新优惠

限时优惠:9月1日-9月22日

30天高级会员仅需29元

1天体验卡首发特惠仅需5.99元

了解详情
不再提醒
插件&应用
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
高级版
套餐订阅购买积分包
AI 工具
文献检索文档翻译深度研究
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2025

Upholding a role for EMT in pancreatic cancer metastasis.

作者信息

Aiello Nicole M, Brabletz Thomas, Kang Yibin, Nieto M Angela, Weinberg Robert A, Stanger Ben Z

机构信息

Departments of Medicine and Cell and Developmental Biology, Abramson Family Cancer Research Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

Experimental Medicine I, Nikolaus-Fiebiger-Center for Molecular Medicine, FAU University of Erlangen-Nuernberg, 91054 Erlangen, Germany.

出版信息

Nature. 2017 Jul 5;547(7661):E7-E8. doi: 10.1038/nature22963.

DOI:10.1038/nature22963
PMID:28682339
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5830071/
Abstract
摘要

相似文献

[1]
Upholding a role for EMT in pancreatic cancer metastasis.

Nature. 2017-7-5

[2]
CCL21/CCR7 Axis Contributed to CD133+ Pancreatic Cancer Stem-Like Cell Metastasis via EMT and Erk/NF-κB Pathway.

PLoS One. 2016-8-9

[3]
Upholding a role for EMT in breast cancer metastasis.

Nature. 2017-7-5

[4]
Girdin interaction with vimentin induces EMT and promotes the growth and metastasis of pancreatic ductal adenocarcinoma.

Oncol Rep. 2020-8

[5]
The EMT-activator Zeb1 is a key factor for cell plasticity and promotes metastasis in pancreatic cancer.

Nat Cell Biol. 2017-4-17

[6]
MiR-301a transcriptionally activated by HIF-2α promotes hypoxia-induced epithelial-mesenchymal transition by targeting TP63 in pancreatic cancer.

World J Gastroenterol. 2020-5-21

[7]
HS-173, a novel PI3K inhibitor suppresses EMT and metastasis in pancreatic cancer.

Oncotarget. 2016-11-22

[8]
The epithelial to mesenchymal transition in pancreatic cancer: A systematic review.

Pancreatology. 2015

[9]
SNAIL induces epithelial-to-mesenchymal transition in a human pancreatic cancer cell line (BxPC3) and promotes distant metastasis and invasiveness in vivo.

Exp Mol Pathol. 2010-6-1

[10]
Role of BCL9L in transforming growth factor-β (TGF-β)-induced epithelial-to-mesenchymal-transition (EMT) and metastasis of pancreatic cancer.

Oncotarget. 2016-11-8

引用本文的文献

[1]
PI3K/AKT/mTOR Axis in Cancer: From Pathogenesis to Treatment.

MedComm (2020). 2025-7-30

[2]
Unveiling the mechanisms and promising molecular targets of curcumin in pancreatic cancer through multi-dimensional data.

Sci Rep. 2025-7-1

[3]
Revisiting the role of cancer-associated fibroblasts in tumor microenvironment.

Front Immunol. 2025-4-17

[4]
Evolutionary fingerprints of epithelial-to-mesenchymal transition.

Nature. 2025-4

[5]
FLT3 is associated with dendritic cell infiltration, tertiary lymphoid structure construction, and predict response to checkpoint inhibitors immunotherapy in solid cancers.

Sci Rep. 2025-1-20

[6]
The impact of epithelial-mesenchymal transition (EMT) induced by metabolic processes and intracellular signaling pathways on chemo-resistance, metastasis, and recurrence in solid tumors.

Cell Commun Signal. 2024-12-2

[7]
CALB2 drives pancreatic cancer metastasis through inflammatory reprogramming of the tumor microenvironment.

J Exp Clin Cancer Res. 2024-10-3

[8]
Systemic Therapy for Metastatic Pancreatic Cancer-Current Landscape and Future Directions.

Curr Oncol. 2024-9-4

[9]
Intricate relationship between cancer stemness, metastasis, and drug resistance.

MedComm (2020). 2024-9-21

[10]
Lack of basic rationale in epithelial-mesenchymal transition and its related concepts.

Cell Biosci. 2024-8-20

本文引用的文献

[1]
Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer.

Nature. 2015-11-26

[2]
Epithelial plasticity: a common theme in embryonic and cancer cells.

Science. 2013-11-8

[3]
EMT and dissemination precede pancreatic tumor formation.

Cell. 2012-1-20

[4]
The ins and outs of the epithelial to mesenchymal transition in health and disease.

Annu Rev Cell Dev Biol. 2011-7-8

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

推荐工具

医学文档翻译智能文献检索