Silva Merea Valeria, Husain Solomon, Sulica Lucian
New York-Presbyterian Hospital, Department of Otolaryngology-Head and Neck Surgery, Weill Cornell Medical College, New York, New York.
Weill Cornell Medical College, New York, New York.
J Voice. 2018 Mar;32(2):249-255. doi: 10.1016/j.jvoice.2017.05.007. Epub 2017 Jul 3.
This study aims to assess the effect of vocal fold injection augmentation (IA) on subsequent medialization laryngoplasty (ML).
A retrospective cohort study with follow-up telephone survey was carried out.
Clinical records of patients with unilateral vocal fold paralysis or paresis (VFP) who underwent ML between April 2006 and March 2015 were reviewed. Patients who underwent IA before ML were compared with patients who did not, with respect to demographic information, symptoms, Voice Handicap Index-10 (VHI-10), etiology of VFP, and revision rate. Among patients undergoing IA, the effects of injection material and of interval from IA to ML on revision rate were assessed. Follow-up telephone surveys were conducted to evaluate long-term outcomes using VHI-10 and a condition-specific questionnaire.
One hundred thirty-five patients (70 male:65 female) with vocal fold paralysis (125) or paresis (10) underwent ML (96 left:39 right). Sixty-six (48.9%) patients underwent concurrent arytenoid adduction. Fourteen (10.4%) patients required revision. Fifty-six (41.5%) patients had prior IA; five (8.9%) patients underwent revision. Seventy-nine (58.5%) patients did not have IA; nine (11.4%) patients required revision (P = 0.78). Neither augmentation material nor length of interval between last IA and ML affected the revision rate (P = 1.00; P ≥ 0.11 for all tested intervals, respectively). No difference in follow-up VHI-10 score was found between patients who had IA before ML and patients who had not (P = 0.73).
IA does not appear to affect the revision rate or long-term outcome of subsequent ML.
本研究旨在评估声带注射填充术（IA）对后续喉内移术（ML）的影响。
开展一项带有随访电话调查的回顾性队列研究。
回顾了2006年4月至2015年3月期间接受ML的单侧声带麻痹或轻瘫（VFP）患者的临床记录。将在ML前接受IA的患者与未接受IA的患者在人口统计学信息、症状、嗓音障碍指数-10（VHI-10）、VFP病因及翻修率方面进行比较。在接受IA的患者中，评估注射材料以及从IA至ML的间隔时间对翻修率的影响。进行随访电话调查，使用VHI-10和特定病情问卷评估长期疗效。
135例（男70例：女65例）声带麻痹（125例）或轻瘫（10例）患者接受了ML（左侧96例：右侧39例）。66例（48.9%）患者同时进行了杓状软骨内收术。14例（10.4%）患者需要翻修。56例（41.5%）患者曾接受IA；5例（8.9%）患者接受了翻修。79例（58.5%）患者未接受IA；9例（11.4%）患者需要翻修（P = 0.78）。填充材料以及最后一次IA与ML之间的间隔时间均未影响翻修率（P = 1.00；所有测试间隔的P值均≥0.11）。在ML前接受IA的患者与未接受IA的患者之间，随访VHI-10评分未发现差异（P = 0.73）。
IA似乎不会影响后续ML的翻修率或长期疗效。
